Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro

The sebaceous gland (SG) has been proposed to be replenished by pools of cells, including a population in the SG base, marked by Blimp1. Here, the authors show that Blimp1+ cells can establish an organoid model of the SG, which is regulated by c-Myc and can recapitulate the early stages of acne vulg...

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Autores principales:	Alona Feldman, Dzmitry Mukha, Itzhak I. Maor, Egor Sedov, Elle Koren, Yahav Yosefzon, Tomer Shlomi, Yaron Fuchs
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/277621f55aff4e1c8b1f5e1e71c79fdf
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spelling	oai:doaj.org-article:277621f55aff4e1c8b1f5e1e71c79fdf2021-12-02T16:58:25ZBlimp1+ cells generate functional mouse sebaceous gland organoids in vitro10.1038/s41467-019-10261-62041-1723https://doaj.org/article/277621f55aff4e1c8b1f5e1e71c79fdf2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10261-6https://doaj.org/toc/2041-1723The sebaceous gland (SG) has been proposed to be replenished by pools of cells, including a population in the SG base, marked by Blimp1. Here, the authors show that Blimp1+ cells can establish an organoid model of the SG, which is regulated by c-Myc and can recapitulate the early stages of acne vulgaris.Alona FeldmanDzmitry MukhaItzhak I. MaorEgor SedovElle KorenYahav YosefzonTomer ShlomiYaron FuchsNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alona Feldman Dzmitry Mukha Itzhak I. Maor Egor Sedov Elle Koren Yahav Yosefzon Tomer Shlomi Yaron Fuchs Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
description	The sebaceous gland (SG) has been proposed to be replenished by pools of cells, including a population in the SG base, marked by Blimp1. Here, the authors show that Blimp1+ cells can establish an organoid model of the SG, which is regulated by c-Myc and can recapitulate the early stages of acne vulgaris.
format	article
author	Alona Feldman Dzmitry Mukha Itzhak I. Maor Egor Sedov Elle Koren Yahav Yosefzon Tomer Shlomi Yaron Fuchs
author_facet	Alona Feldman Dzmitry Mukha Itzhak I. Maor Egor Sedov Elle Koren Yahav Yosefzon Tomer Shlomi Yaron Fuchs
author_sort	Alona Feldman
title	Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
title_short	Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
title_full	Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
title_fullStr	Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
title_full_unstemmed	Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
title_sort	blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/277621f55aff4e1c8b1f5e1e71c79fdf
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Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro

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