Multifunctional materials for bone cancer treatment

Catarina Marques,1 José MF Ferreira,1 Ecaterina Andronescu,2 Denisa Ficai,2 Maria Sonmez,3 Anton Ficai21Department of Materials and Ceramics Engineering, Centre for Research in Ceramics and Composite Materials, University of Aveiro, Aveiro, Portugal; 2Faculty of Applied Chemistry and Mat...

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Autores principales:	Marques C, Ferreira JMF, Andronescu E, Ficai D, Sonmez M, Ficai A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/27762271082f49d48942f2de62751779
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spelling	oai:doaj.org-article:27762271082f49d48942f2de627517792021-12-02T00:57:28ZMultifunctional materials for bone cancer treatment1178-2013https://doaj.org/article/27762271082f49d48942f2de627517792014-05-01T00:00:00Zhttp://www.dovepress.com/multifunctional-materials-for-bone-cancer-treatment-a17028https://doaj.org/toc/1178-2013 Catarina Marques,1 José MF Ferreira,1 Ecaterina Andronescu,2 Denisa Ficai,2 Maria Sonmez,3 Anton Ficai21Department of Materials and Ceramics Engineering, Centre for Research in Ceramics and Composite Materials, University of Aveiro, Aveiro, Portugal; 2Faculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, Bucharest, Romania; 3National Research and Development Institute for Textiles and Leather, Bucharest, RomaniaAbstract: The purpose of this review is to present the most recent findings in bone tissue engineering. Special attention is given to multifunctional materials based on collagen and collagen–hydroxyapatite composites used for skin and bone cancer treatments. The multifunctionality of these materials was obtained by adding to the base regenerative grafts proper components, such as ferrites (magnetite being the most important representative), cytostatics (cisplatin, carboplatin, vincristine, methotrexate, paclitaxel, doxorubicin), silver nanoparticles, antibiotics (anthracyclines, geldanamycin), and/or analgesics (ibuprofen, fentanyl). The suitability of complex systems for the intended applications was systematically analyzed. The developmental possibilities of multifunctional materials with regenerative and curative roles (antitumoral as well as pain management) in the field of skin and bone cancer treatment are discussed. It is worth mentioning that better materials are likely to be developed by combining conventional and unconventional experimental strategies.Keywords: bone graft, cancer, collagen, magnetite, cytostatics, silverMarques CFerreira JMFAndronescu EFicai DSonmez MFicai ADove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2014, Iss Issue 1, Pp 2713-2725 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Marques C Ferreira JMF Andronescu E Ficai D Sonmez M Ficai A Multifunctional materials for bone cancer treatment
description	Catarina Marques,1 José MF Ferreira,1 Ecaterina Andronescu,2 Denisa Ficai,2 Maria Sonmez,3 Anton Ficai21Department of Materials and Ceramics Engineering, Centre for Research in Ceramics and Composite Materials, University of Aveiro, Aveiro, Portugal; 2Faculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, Bucharest, Romania; 3National Research and Development Institute for Textiles and Leather, Bucharest, RomaniaAbstract: The purpose of this review is to present the most recent findings in bone tissue engineering. Special attention is given to multifunctional materials based on collagen and collagen–hydroxyapatite composites used for skin and bone cancer treatments. The multifunctionality of these materials was obtained by adding to the base regenerative grafts proper components, such as ferrites (magnetite being the most important representative), cytostatics (cisplatin, carboplatin, vincristine, methotrexate, paclitaxel, doxorubicin), silver nanoparticles, antibiotics (anthracyclines, geldanamycin), and/or analgesics (ibuprofen, fentanyl). The suitability of complex systems for the intended applications was systematically analyzed. The developmental possibilities of multifunctional materials with regenerative and curative roles (antitumoral as well as pain management) in the field of skin and bone cancer treatment are discussed. It is worth mentioning that better materials are likely to be developed by combining conventional and unconventional experimental strategies.Keywords: bone graft, cancer, collagen, magnetite, cytostatics, silver
format	article
author	Marques C Ferreira JMF Andronescu E Ficai D Sonmez M Ficai A
author_facet	Marques C Ferreira JMF Andronescu E Ficai D Sonmez M Ficai A
author_sort	Marques C
title	Multifunctional materials for bone cancer treatment
title_short	Multifunctional materials for bone cancer treatment
title_full	Multifunctional materials for bone cancer treatment
title_fullStr	Multifunctional materials for bone cancer treatment
title_full_unstemmed	Multifunctional materials for bone cancer treatment
title_sort	multifunctional materials for bone cancer treatment
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/27762271082f49d48942f2de62751779
work_keys_str_mv	AT marquesc multifunctionalmaterialsforbonecancertreatment AT ferreirajmf multifunctionalmaterialsforbonecancertreatment AT andronescue multifunctionalmaterialsforbonecancertreatment AT ficaid multifunctionalmaterialsforbonecancertreatment AT sonmezm multifunctionalmaterialsforbonecancertreatment AT ficaia multifunctionalmaterialsforbonecancertreatment
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Multifunctional materials for bone cancer treatment

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