Association of GHR|AluI gene polymorphism with body weight parameters in Grati-PO cattle

The growth hormone receptor (GHR) gene is member of the class I cytokine receptor family that important in growth regulation including in cattle. This study aimed to analyze the association between GHR|AluI gene with body weight, parameters in Grati-PO cattle population. A total of 304 blood samples...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	H. Hartati, A.A.R. Hapsari, B. D. P. Soewandi, S. Anwar, S. P. Rahmadani, A. Aryogi, D. Pamungkas
Formato:	article
Lenguaje:	EN
Publicado:	Diponegoro University, Faculty of Animal and Agricultural Sciences 2021
Materias:	body weight growth hormone receptor polymorphism po-grati cattle Animal culture SF1-1100 Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/27886fae9e564ea7a74c146d75cb8924
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:27886fae9e564ea7a74c146d75cb8924
record_format	dspace
spelling	oai:doaj.org-article:27886fae9e564ea7a74c146d75cb89242021-12-02T20:46:58ZAssociation of GHR\|AluI gene polymorphism with body weight parameters in Grati-PO cattle2087-82732460-627810.14710/jitaa.46.4.272-281https://doaj.org/article/27886fae9e564ea7a74c146d75cb89242021-12-01T00:00:00Zhttps://ejournal.undip.ac.id/index.php/jitaa/article/view/36665https://doaj.org/toc/2087-8273https://doaj.org/toc/2460-6278The growth hormone receptor (GHR) gene is member of the class I cytokine receptor family that important in growth regulation including in cattle. This study aimed to analyze the association between GHR\|AluI gene with body weight, parameters in Grati-PO cattle population. A total of 304 blood samples were collected from the experimental station at the Beef Cattle Research Station, which were also equipped with 304 phenotypic data. DNA was extracted using a zymo extraction kit. Detection of of the polymorphism of GHR gene using PCR-RFLP method with AluI restriction enzymes. polymorphism indicators include genotype frequency, allele frequency, Hardy-Weinberg Equilibrium, observed heterozygosity (Ho), expected heterozygosity (He), polymorphism information content (PIC) and number of effective alleles (Ne). Association analysis was carried out using a linear mixed model. The performance of birth weight, weaning weight, yearling weight and 18 months weight were 25.4 + 0.2 kg; 113.8 + 2.3 kg; 159.9 + 2.7 kg and 213.7 + 3.6 kg, respectively. The result of association analysis was significant (P<0.05) on weaning weight, yearling weight and 18 months weight. It could be concluded that the GHR gene has potential to be a candidate genetic marker for growth traits in Grati-PO cattle.H. HartatiA.A.R. HapsariB. D. P. SoewandiS. AnwarS. P. RahmadaniA. AryogiD. PamungkasDiponegoro University, Faculty of Animal and Agricultural Sciencesarticlebody weightgrowth hormone receptorpolymorphismpo-grati cattleAnimal cultureSF1-1100Veterinary medicineSF600-1100ENJournal of the Indonesian Tropical Animal Agriculture, Vol 46, Iss 4, Pp 272-281 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	body weight growth hormone receptor polymorphism po-grati cattle Animal culture SF1-1100 Veterinary medicine SF600-1100
spellingShingle	body weight growth hormone receptor polymorphism po-grati cattle Animal culture SF1-1100 Veterinary medicine SF600-1100 H. Hartati A.A.R. Hapsari B. D. P. Soewandi S. Anwar S. P. Rahmadani A. Aryogi D. Pamungkas Association of GHR\|AluI gene polymorphism with body weight parameters in Grati-PO cattle
description	The growth hormone receptor (GHR) gene is member of the class I cytokine receptor family that important in growth regulation including in cattle. This study aimed to analyze the association between GHR\|AluI gene with body weight, parameters in Grati-PO cattle population. A total of 304 blood samples were collected from the experimental station at the Beef Cattle Research Station, which were also equipped with 304 phenotypic data. DNA was extracted using a zymo extraction kit. Detection of of the polymorphism of GHR gene using PCR-RFLP method with AluI restriction enzymes. polymorphism indicators include genotype frequency, allele frequency, Hardy-Weinberg Equilibrium, observed heterozygosity (Ho), expected heterozygosity (He), polymorphism information content (PIC) and number of effective alleles (Ne). Association analysis was carried out using a linear mixed model. The performance of birth weight, weaning weight, yearling weight and 18 months weight were 25.4 + 0.2 kg; 113.8 + 2.3 kg; 159.9 + 2.7 kg and 213.7 + 3.6 kg, respectively. The result of association analysis was significant (P<0.05) on weaning weight, yearling weight and 18 months weight. It could be concluded that the GHR gene has potential to be a candidate genetic marker for growth traits in Grati-PO cattle.
format	article
author	H. Hartati A.A.R. Hapsari B. D. P. Soewandi S. Anwar S. P. Rahmadani A. Aryogi D. Pamungkas
author_facet	H. Hartati A.A.R. Hapsari B. D. P. Soewandi S. Anwar S. P. Rahmadani A. Aryogi D. Pamungkas
author_sort	H. Hartati
title	Association of GHR\|AluI gene polymorphism with body weight parameters in Grati-PO cattle
title_short	Association of GHR\|AluI gene polymorphism with body weight parameters in Grati-PO cattle
title_full	Association of GHR\|AluI gene polymorphism with body weight parameters in Grati-PO cattle
title_fullStr	Association of GHR\|AluI gene polymorphism with body weight parameters in Grati-PO cattle
title_full_unstemmed	Association of GHR\|AluI gene polymorphism with body weight parameters in Grati-PO cattle
title_sort	association of ghr\|alui gene polymorphism with body weight parameters in grati-po cattle
publisher	Diponegoro University, Faculty of Animal and Agricultural Sciences
publishDate	2021
url	https://doaj.org/article/27886fae9e564ea7a74c146d75cb8924
work_keys_str_mv	AT hhartati associationofghraluigenepolymorphismwithbodyweightparametersingratipocattle AT aarhapsari associationofghraluigenepolymorphismwithbodyweightparametersingratipocattle AT bdpsoewandi associationofghraluigenepolymorphismwithbodyweightparametersingratipocattle AT sanwar associationofghraluigenepolymorphismwithbodyweightparametersingratipocattle AT sprahmadani associationofghraluigenepolymorphismwithbodyweightparametersingratipocattle AT aaryogi associationofghraluigenepolymorphismwithbodyweightparametersingratipocattle AT dpamungkas associationofghraluigenepolymorphismwithbodyweightparametersingratipocattle
_version_	1718374038541172736

Association of GHR|AluI gene polymorphism with body weight parameters in Grati-PO cattle

Ejemplares similares