Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism

Cardiac tamponade is a medical emergency and must be managed promptly, and reaching a diagnosis is imperative to prevent recurrence. Herein, we present a case of a young female patient that presented with progressive shortness of breath and abdominal distension and was found to have cardiac tamponad...

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Autores principales: Moaaz Baghal, Viralkumar Amrutiya, Bhoomi Patel, Rutwik Patel, Jonathan Hernandez, Mohamed Ahmed, Abraham Lo, Mark Gabelman
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Lenguaje:EN
Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/2790800213ce4670a2bcc90f8bad8680
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spelling oai:doaj.org-article:2790800213ce4670a2bcc90f8bad86802021-11-22T01:09:41ZPericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism2090-641210.1155/2021/2666601https://doaj.org/article/2790800213ce4670a2bcc90f8bad86802021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/2666601https://doaj.org/toc/2090-6412Cardiac tamponade is a medical emergency and must be managed promptly, and reaching a diagnosis is imperative to prevent recurrence. Herein, we present a case of a young female patient that presented with progressive shortness of breath and abdominal distension and was found to have cardiac tamponade with the finding of elevation of a blood tumor marker, CA-125, in the setting of nonadherence to thyroid replacement therapy. She was managed by surgical pericardial window and abdominal paracentesis, with replacement of thyroid hormones leading to resolution of the tamponade and ascites. CA-125 elevation associated with cardiac tamponade and myxedema ascites due to hypothyroidism is very rare, and we aim to shed light on the importance of having a broad differential when approaching cardiac tamponade and understand the association between CA-125 and hypothyroidism.Moaaz BaghalViralkumar AmrutiyaBhoomi PatelRutwik PatelJonathan HernandezMohamed AhmedAbraham LoMark GabelmanHindawi LimitedarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENCase Reports in Cardiology, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Moaaz Baghal
Viralkumar Amrutiya
Bhoomi Patel
Rutwik Patel
Jonathan Hernandez
Mohamed Ahmed
Abraham Lo
Mark Gabelman
Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
description Cardiac tamponade is a medical emergency and must be managed promptly, and reaching a diagnosis is imperative to prevent recurrence. Herein, we present a case of a young female patient that presented with progressive shortness of breath and abdominal distension and was found to have cardiac tamponade with the finding of elevation of a blood tumor marker, CA-125, in the setting of nonadherence to thyroid replacement therapy. She was managed by surgical pericardial window and abdominal paracentesis, with replacement of thyroid hormones leading to resolution of the tamponade and ascites. CA-125 elevation associated with cardiac tamponade and myxedema ascites due to hypothyroidism is very rare, and we aim to shed light on the importance of having a broad differential when approaching cardiac tamponade and understand the association between CA-125 and hypothyroidism.
format article
author Moaaz Baghal
Viralkumar Amrutiya
Bhoomi Patel
Rutwik Patel
Jonathan Hernandez
Mohamed Ahmed
Abraham Lo
Mark Gabelman
author_facet Moaaz Baghal
Viralkumar Amrutiya
Bhoomi Patel
Rutwik Patel
Jonathan Hernandez
Mohamed Ahmed
Abraham Lo
Mark Gabelman
author_sort Moaaz Baghal
title Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
title_short Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
title_full Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
title_fullStr Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
title_full_unstemmed Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
title_sort pericardial tamponade and elevated serum ca-125 level in inadequately treated hypothyroidism
publisher Hindawi Limited
publishDate 2021
url https://doaj.org/article/2790800213ce4670a2bcc90f8bad8680
work_keys_str_mv AT moaazbaghal pericardialtamponadeandelevatedserumca125levelininadequatelytreatedhypothyroidism
AT viralkumaramrutiya pericardialtamponadeandelevatedserumca125levelininadequatelytreatedhypothyroidism
AT bhoomipatel pericardialtamponadeandelevatedserumca125levelininadequatelytreatedhypothyroidism
AT rutwikpatel pericardialtamponadeandelevatedserumca125levelininadequatelytreatedhypothyroidism
AT jonathanhernandez pericardialtamponadeandelevatedserumca125levelininadequatelytreatedhypothyroidism
AT mohamedahmed pericardialtamponadeandelevatedserumca125levelininadequatelytreatedhypothyroidism
AT abrahamlo pericardialtamponadeandelevatedserumca125levelininadequatelytreatedhypothyroidism
AT markgabelman pericardialtamponadeandelevatedserumca125levelininadequatelytreatedhypothyroidism
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