A case of HPV-53-related cervical cancer in an elderly patient
Marusya Lieveld,1 Elizaveta Padalko,2,3 Marleen Praet,4 Davy Vanden Broeck1 1Department of Uro/gynaecology, Ghent University Hospital, Ghent, Belgium; 2Department of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent, Belgium; 3School of Life Sciences, Hasselt Univers...
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Dove Medical Press
2014
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oai:doaj.org-article:279245116601433cb6a5936270b50c782021-12-02T04:54:03ZA case of HPV-53-related cervical cancer in an elderly patient1178-1998https://doaj.org/article/279245116601433cb6a5936270b50c782014-11-01T00:00:00Zhttps://www.dovepress.com/a-case-of-hpv-53-related-cervical-cancer-in-an-elderly-patient-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Marusya Lieveld,1 Elizaveta Padalko,2,3 Marleen Praet,4 Davy Vanden Broeck1 1Department of Uro/gynaecology, Ghent University Hospital, Ghent, Belgium; 2Department of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent, Belgium; 3School of Life Sciences, Hasselt University, Diepenbeek, Belgium; 4N. Goormaghtigh Institute of Pathology, Ghent University Hospital, Ghent, BelgiumZappacosta et al1 recently published a case report concerning a human papillomavirus (HPV)-positive invasive cervical cancer in a 79-year-old women who had a history of normal Pap smears. In this article, Anyplex II HPV28 (Seegene) is used for HPV genotyping of formalin-fixed paraffin embedded (FFPE) tissue, liquid based cytology (LBC) specimens and urine samples. It is suggested that HPV53 is present exclusively in the cervical cancer cells, lymph node metastases, and atypical urinary cells of one single case while the surrounding CIN2+ tissue revealed ten different HPV strains. Unfortunately, the HPV genotype results for lymph nodes and urinary cells are not presented while these results underline the potential role of HPV53 in oncogenesis. Moreover, it is generally accepted that one lesion is caused by one HPV infection, detection of multiple HPV types thus indicates the presence of multiple infections,2 suggesting that this patient may have several lesions. Read the original article Lieveld MPadalko EPraet MVanden Broeck DDove Medical PressarticleHPV53HRMcervical cancerAnyplex II HPV 28GeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 1933-1938 (2014) |
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HPV53 HRM cervical cancer Anyplex II HPV 28 Geriatrics RC952-954.6 |
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HPV53 HRM cervical cancer Anyplex II HPV 28 Geriatrics RC952-954.6 Lieveld M Padalko E Praet M Vanden Broeck D A case of HPV-53-related cervical cancer in an elderly patient |
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Marusya Lieveld,1 Elizaveta Padalko,2,3 Marleen Praet,4 Davy Vanden Broeck1 1Department of Uro/gynaecology, Ghent University Hospital, Ghent, Belgium; 2Department of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent, Belgium; 3School of Life Sciences, Hasselt University, Diepenbeek, Belgium; 4N. Goormaghtigh Institute of Pathology, Ghent University Hospital, Ghent, BelgiumZappacosta et al1 recently published a case report concerning a human papillomavirus (HPV)-positive invasive cervical cancer in a 79-year-old women who had a history of normal Pap smears. In this article, Anyplex II HPV28 (Seegene) is used for HPV genotyping of formalin-fixed paraffin embedded (FFPE) tissue, liquid based cytology (LBC) specimens and urine samples. It is suggested that HPV53 is present exclusively in the cervical cancer cells, lymph node metastases, and atypical urinary cells of one single case while the surrounding CIN2+ tissue revealed ten different HPV strains. Unfortunately, the HPV genotype results for lymph nodes and urinary cells are not presented while these results underline the potential role of HPV53 in oncogenesis. Moreover, it is generally accepted that one lesion is caused by one HPV infection, detection of multiple HPV types thus indicates the presence of multiple infections,2 suggesting that this patient may have several lesions. Read the original article |
format |
article |
author |
Lieveld M Padalko E Praet M Vanden Broeck D |
author_facet |
Lieveld M Padalko E Praet M Vanden Broeck D |
author_sort |
Lieveld M |
title |
A case of HPV-53-related cervical cancer in an elderly patient |
title_short |
A case of HPV-53-related cervical cancer in an elderly patient |
title_full |
A case of HPV-53-related cervical cancer in an elderly patient |
title_fullStr |
A case of HPV-53-related cervical cancer in an elderly patient |
title_full_unstemmed |
A case of HPV-53-related cervical cancer in an elderly patient |
title_sort |
case of hpv-53-related cervical cancer in an elderly patient |
publisher |
Dove Medical Press |
publishDate |
2014 |
url |
https://doaj.org/article/279245116601433cb6a5936270b50c78 |
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