Comparing measurement properties of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients

Abstract Background The adult versions EQ-5D-3L and EQ-5D-5L have been extensive compared. This is not the case for the EQ-5D youth versions. The study aim was to compare the measurement properties and responsiveness of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients. Methods A sample of patients 8...

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Autores principales:	Titi Sahidah Fitriana, Fredrick Dermawan Purba, Rina Rahmatika, Riski Muhaimin, Nur Melani Sari, Gouke Bonsel, Elly Stolk, Jan J. V. Busschbach
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	EQ-5D-Y-5L EQ-5D-Y-3L paediatric patients Psychometrics Health-related quality of life Computer applications to medicine. Medical informatics R858-859.7
Acceso en línea:	https://doaj.org/article/2796dd6099fd4ccda95ea6f79226bce0
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spelling	oai:doaj.org-article:2796dd6099fd4ccda95ea6f79226bce02021-11-21T12:28:08ZComparing measurement properties of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients10.1186/s12955-021-01889-41477-7525https://doaj.org/article/2796dd6099fd4ccda95ea6f79226bce02021-11-01T00:00:00Zhttps://doi.org/10.1186/s12955-021-01889-4https://doaj.org/toc/1477-7525Abstract Background The adult versions EQ-5D-3L and EQ-5D-5L have been extensive compared. This is not the case for the EQ-5D youth versions. The study aim was to compare the measurement properties and responsiveness of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients. Methods A sample of patients 8–16 years old with different diseases and a wide range of disease severity was asked to complete EQ-5D-Y-3L, EQ-5D-Y-5L, PedsQL Generic Core Scale, and selected, appropriate disease-specific instruments, three times. EQ-5D-Y-3L and EQ-5D-Y-5L were compared in terms of: feasibility, (re-)distribution properties, discriminatory power, convergent validity, test–retest reliability, and responsiveness. Results 286 participating patients suffered from one of the following diseases: major beta-thalassemia, haemophilia, acute lymphoblastic leukaemia, acute illness. Missing responses were comparable between versions of the EQ-5D-Y, suggesting comparable feasibility. The number of patients in the best health state (level profile 11111) was equal in both EQ-5D-Y versions. The projection of EQ-5D-Y-3L scores onto EQ-5D-Y-5L for all dimensions showed that the two additional levels in EQ-5D-Y-5L slightly improved the accuracy of patients in reporting their problems, especially if severe. Convergent validity with PedsQL and disease-specific measures showed that the two EQ-5D-Y versions performed about equally. Test–retest reliability (EQ-5D-Y-3L 0.78 vs EQ-5D-Y-5L 0.84), and sensitivity for detecting health changes, were both better in EQ-5D-Y-5L. Conclusions Extending the number of levels did not give clear superiority to EQ-5D-Y-5L over EQ-5D-Y-3L based on the criteria assessed in this study. However, increasing the number of levels benefitted EQ-5D-Y performance in the measurement of moderate to severe problems and especially in longitudinal study designs.Titi Sahidah FitrianaFredrick Dermawan PurbaRina RahmatikaRiski MuhaiminNur Melani SariGouke BonselElly StolkJan J. V. BusschbachBMCarticleEQ-5D-Y-5LEQ-5D-Y-3L paediatric patientsPsychometricsHealth-related quality of lifeComputer applications to medicine. Medical informaticsR858-859.7ENHealth and Quality of Life Outcomes, Vol 19, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	EQ-5D-Y-5L EQ-5D-Y-3L paediatric patients Psychometrics Health-related quality of life Computer applications to medicine. Medical informatics R858-859.7
spellingShingle	EQ-5D-Y-5L EQ-5D-Y-3L paediatric patients Psychometrics Health-related quality of life Computer applications to medicine. Medical informatics R858-859.7 Titi Sahidah Fitriana Fredrick Dermawan Purba Rina Rahmatika Riski Muhaimin Nur Melani Sari Gouke Bonsel Elly Stolk Jan J. V. Busschbach Comparing measurement properties of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients
description	Abstract Background The adult versions EQ-5D-3L and EQ-5D-5L have been extensive compared. This is not the case for the EQ-5D youth versions. The study aim was to compare the measurement properties and responsiveness of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients. Methods A sample of patients 8–16 years old with different diseases and a wide range of disease severity was asked to complete EQ-5D-Y-3L, EQ-5D-Y-5L, PedsQL Generic Core Scale, and selected, appropriate disease-specific instruments, three times. EQ-5D-Y-3L and EQ-5D-Y-5L were compared in terms of: feasibility, (re-)distribution properties, discriminatory power, convergent validity, test–retest reliability, and responsiveness. Results 286 participating patients suffered from one of the following diseases: major beta-thalassemia, haemophilia, acute lymphoblastic leukaemia, acute illness. Missing responses were comparable between versions of the EQ-5D-Y, suggesting comparable feasibility. The number of patients in the best health state (level profile 11111) was equal in both EQ-5D-Y versions. The projection of EQ-5D-Y-3L scores onto EQ-5D-Y-5L for all dimensions showed that the two additional levels in EQ-5D-Y-5L slightly improved the accuracy of patients in reporting their problems, especially if severe. Convergent validity with PedsQL and disease-specific measures showed that the two EQ-5D-Y versions performed about equally. Test–retest reliability (EQ-5D-Y-3L 0.78 vs EQ-5D-Y-5L 0.84), and sensitivity for detecting health changes, were both better in EQ-5D-Y-5L. Conclusions Extending the number of levels did not give clear superiority to EQ-5D-Y-5L over EQ-5D-Y-3L based on the criteria assessed in this study. However, increasing the number of levels benefitted EQ-5D-Y performance in the measurement of moderate to severe problems and especially in longitudinal study designs.
format	article
author	Titi Sahidah Fitriana Fredrick Dermawan Purba Rina Rahmatika Riski Muhaimin Nur Melani Sari Gouke Bonsel Elly Stolk Jan J. V. Busschbach
author_facet	Titi Sahidah Fitriana Fredrick Dermawan Purba Rina Rahmatika Riski Muhaimin Nur Melani Sari Gouke Bonsel Elly Stolk Jan J. V. Busschbach
author_sort	Titi Sahidah Fitriana
title	Comparing measurement properties of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients
title_short	Comparing measurement properties of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients
title_full	Comparing measurement properties of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients
title_fullStr	Comparing measurement properties of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients
title_full_unstemmed	Comparing measurement properties of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients
title_sort	comparing measurement properties of eq-5d-y-3l and eq-5d-y-5l in paediatric patients
publisher	BMC
publishDate	2021
url	https://doaj.org/article/2796dd6099fd4ccda95ea6f79226bce0
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Comparing measurement properties of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients

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