Plastic processes at ischemic injury of myocardium and role of local mitogens in its regeneration (according to the results of researches made in Scientific Center of Reconstructive and Restorative Surgery SB RAMS)

The work presents the basic results of researches of Scientific Center of Reconstructive and Restorative Surgery SB RAMS on the issue of influence of growth factors on postinfarction remodeling of myocardium. It has been shown, that the researches defined the significance of vascular endothelial gro...

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Autores principales:	N. I. Arsentyeva, M. A. Makarova, M. L. Arsentyeva
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2014
Materias:	vegf fgf myocardial infarction postinfarction cardiosclerosis growth factors regeneration Science Q
Acceso en línea:	https://doaj.org/article/279bf06c6d1742d289a4eee8c3b018d1
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spelling	oai:doaj.org-article:279bf06c6d1742d289a4eee8c3b018d12021-11-23T06:14:30ZPlastic processes at ischemic injury of myocardium and role of local mitogens in its regeneration (according to the results of researches made in Scientific Center of Reconstructive and Restorative Surgery SB RAMS)2541-94202587-9596https://doaj.org/article/279bf06c6d1742d289a4eee8c3b018d12014-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1775https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The work presents the basic results of researches of Scientific Center of Reconstructive and Restorative Surgery SB RAMS on the issue of influence of growth factors on postinfarction remodeling of myocardium. It has been shown, that the researches defined the significance of vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF) for myocardium reparation after its ischemic damage. There is a description of mechanisms of regulation of bloodflow in distal parts of coronary vasculature by endothelin on different stages of formation of postinfarction cardiosclerosis. Quantitative characteristics is given of mitogens level dynamics, cell composition and activity of developing connective-tissue component in various parts of myocardium on stages of reparation after ischemic damage. The article also contains substantiation of perspective of management of growth factors dynamic for providing optimal parameters of regeneration area and improvement of pathological process outcomes.N. I. ArsentyevaM. A. MakarovaM. L. ArsentyevaScientific Сentre for Family Health and Human Reproduction Problemsarticlevegffgfmyocardial infarctionpostinfarction cardiosclerosisgrowth factorsvegffgfregenerationScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3, Pp 116-121 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	vegf fgf myocardial infarction postinfarction cardiosclerosis growth factors vegf fgf regeneration Science Q
spellingShingle	vegf fgf myocardial infarction postinfarction cardiosclerosis growth factors vegf fgf regeneration Science Q N. I. Arsentyeva M. A. Makarova M. L. Arsentyeva Plastic processes at ischemic injury of myocardium and role of local mitogens in its regeneration (according to the results of researches made in Scientific Center of Reconstructive and Restorative Surgery SB RAMS)
description	The work presents the basic results of researches of Scientific Center of Reconstructive and Restorative Surgery SB RAMS on the issue of influence of growth factors on postinfarction remodeling of myocardium. It has been shown, that the researches defined the significance of vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF) for myocardium reparation after its ischemic damage. There is a description of mechanisms of regulation of bloodflow in distal parts of coronary vasculature by endothelin on different stages of formation of postinfarction cardiosclerosis. Quantitative characteristics is given of mitogens level dynamics, cell composition and activity of developing connective-tissue component in various parts of myocardium on stages of reparation after ischemic damage. The article also contains substantiation of perspective of management of growth factors dynamic for providing optimal parameters of regeneration area and improvement of pathological process outcomes.
format	article
author	N. I. Arsentyeva M. A. Makarova M. L. Arsentyeva
author_facet	N. I. Arsentyeva M. A. Makarova M. L. Arsentyeva
author_sort	N. I. Arsentyeva
title	Plastic processes at ischemic injury of myocardium and role of local mitogens in its regeneration (according to the results of researches made in Scientific Center of Reconstructive and Restorative Surgery SB RAMS)
title_short	Plastic processes at ischemic injury of myocardium and role of local mitogens in its regeneration (according to the results of researches made in Scientific Center of Reconstructive and Restorative Surgery SB RAMS)
title_full	Plastic processes at ischemic injury of myocardium and role of local mitogens in its regeneration (according to the results of researches made in Scientific Center of Reconstructive and Restorative Surgery SB RAMS)
title_fullStr	Plastic processes at ischemic injury of myocardium and role of local mitogens in its regeneration (according to the results of researches made in Scientific Center of Reconstructive and Restorative Surgery SB RAMS)
title_full_unstemmed	Plastic processes at ischemic injury of myocardium and role of local mitogens in its regeneration (according to the results of researches made in Scientific Center of Reconstructive and Restorative Surgery SB RAMS)
title_sort	plastic processes at ischemic injury of myocardium and role of local mitogens in its regeneration (according to the results of researches made in scientific center of reconstructive and restorative surgery sb rams)
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2014
url	https://doaj.org/article/279bf06c6d1742d289a4eee8c3b018d1
work_keys_str_mv	AT niarsentyeva plasticprocessesatischemicinjuryofmyocardiumandroleoflocalmitogensinitsregenerationaccordingtotheresultsofresearchesmadeinscientificcenterofreconstructiveandrestorativesurgerysbrams AT mamakarova plasticprocessesatischemicinjuryofmyocardiumandroleoflocalmitogensinitsregenerationaccordingtotheresultsofresearchesmadeinscientificcenterofreconstructiveandrestorativesurgerysbrams AT mlarsentyeva plasticprocessesatischemicinjuryofmyocardiumandroleoflocalmitogensinitsregenerationaccordingtotheresultsofresearchesmadeinscientificcenterofreconstructiveandrestorativesurgerysbrams
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Plastic processes at ischemic injury of myocardium and role of local mitogens in its regeneration (according to the results of researches made in Scientific Center of Reconstructive and Restorative Surgery SB RAMS)

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