Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection
ABSTRACT With over 3.5 billion people at risk and approximately 390 million human infections per year, dengue virus (DENV) disease strains health care resources worldwide. Previously, we and others established models for DENV pathogenesis in mice that completely lack subunits of the receptors (Ifnar...
Guardado en:
Autores principales: | Amelia K. Pinto, James D. Brien, Chia-Ying Kao Lam, Syd Johnson, Cindy Chiang, John Hiscott, Vanessa V. Sarathy, Alan D. Barrett, Sujan Shresta, Michael S. Diamond |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2015
|
Materias: | |
Acceso en línea: | https://doaj.org/article/27a57dee613941a18b597207c172d473 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Role of Complement in Dengue Virus Infection: Protection or Pathogenesis?
por: Sujan Shresta
Publicado: (2012) -
Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge
por: Jinsheng Wen, et al.
Publicado: (2017) -
The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1.
por: Bimmi Shrestha, et al.
Publicado: (2010) -
Repeated exposure to dengue virus elicits robust cross neutralizing antibodies against Zika virus in residents of Northeastern Thailand
por: Sararat Hattakam, et al.
Publicado: (2021) -
Cross-reactive Dengue virus-specific CD8+ T cells protect against Zika virus during pregnancy
por: Jose Angel Regla-Nava, et al.
Publicado: (2018)