Interferons and their potential in the treatment of ocular inflammation

Friederike Mackensen,1 Regina Max,2 Matthias D Becker31Department of Ophthalmology, 2Department of Internal Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Germany; 3Department of Ophthalmology, Triemli Hospital Z&uuml;rich, SwitzerlandAbstract: Since their discovery in...

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Autores principales:	Friederike Mackensen, Regina Max, Matthias D Becker
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2009
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/27a5ac58a7d34d6388f9f285083fd66d
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spelling	oai:doaj.org-article:27a5ac58a7d34d6388f9f285083fd66d2021-12-02T02:53:15ZInterferons and their potential in the treatment of ocular inflammation1177-54671177-5483https://doaj.org/article/27a5ac58a7d34d6388f9f285083fd66d2009-10-01T00:00:00Zhttp://www.dovepress.com/interferons-and-their-potential-in-the-treatment-of-ocular-inflammatio-a3639https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Friederike Mackensen,1 Regina Max,2 Matthias D Becker31Department of Ophthalmology, 2Department of Internal Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Germany; 3Department of Ophthalmology, Triemli Hospital Z&uuml;rich, SwitzerlandAbstract: Since their discovery in the 1950s interferons have been the scope of investigation in many diseases as therapeutic as well as pathogenetic factors. We know they have immune stimulatory and immune regulatory effects. This apparently counter-intuitive mechanism can be summarized as immunomodulatory action and seems to be very effective in a number of ocular inflammatory diseases. We review the current knowledge of interferons in immunity and autoimmunity and show their use in clinical ophthalmologic practice.Keywords: interferon, uveitis, treatment, inflammation Friederike MackensenRegina MaxMatthias D BeckerDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2009, Iss default, Pp 559-566 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Friederike Mackensen Regina Max Matthias D Becker Interferons and their potential in the treatment of ocular inflammation
description	Friederike Mackensen,1 Regina Max,2 Matthias D Becker31Department of Ophthalmology, 2Department of Internal Medicine, Interdisciplinary Uveitis Center, University of Heidelberg, Germany; 3Department of Ophthalmology, Triemli Hospital Z&uuml;rich, SwitzerlandAbstract: Since their discovery in the 1950s interferons have been the scope of investigation in many diseases as therapeutic as well as pathogenetic factors. We know they have immune stimulatory and immune regulatory effects. This apparently counter-intuitive mechanism can be summarized as immunomodulatory action and seems to be very effective in a number of ocular inflammatory diseases. We review the current knowledge of interferons in immunity and autoimmunity and show their use in clinical ophthalmologic practice.Keywords: interferon, uveitis, treatment, inflammation
format	article
author	Friederike Mackensen Regina Max Matthias D Becker
author_facet	Friederike Mackensen Regina Max Matthias D Becker
author_sort	Friederike Mackensen
title	Interferons and their potential in the treatment of ocular inflammation
title_short	Interferons and their potential in the treatment of ocular inflammation
title_full	Interferons and their potential in the treatment of ocular inflammation
title_fullStr	Interferons and their potential in the treatment of ocular inflammation
title_full_unstemmed	Interferons and their potential in the treatment of ocular inflammation
title_sort	interferons and their potential in the treatment of ocular inflammation
publisher	Dove Medical Press
publishDate	2009
url	https://doaj.org/article/27a5ac58a7d34d6388f9f285083fd66d
work_keys_str_mv	AT friederikemackensen interferonsandtheirpotentialinthetreatmentofocularinflammation AT reginamax interferonsandtheirpotentialinthetreatmentofocularinflammation AT matthiasdbecker interferonsandtheirpotentialinthetreatmentofocularinflammation
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Interferons and their potential in the treatment of ocular inflammation

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