Population pharmacokinetic analysis of doripenem for Japanese patients in intensive care unit

Abstract We aimed to construct a novel population pharmacokinetics (PPK) model of doripenem (DRPM) for Japanese patients in intensive care unit, incorporating the clearance of DRPM by continuous renal replacement therapy (CRRT). Twenty-one patients treated with DRPM (0.25 or 0.5 g) by intravenous in...

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Détails bibliographiques
Auteurs principaux: Ko Nonoshita, Yosuke Suzuki, Ryota Tanaka, Tetsuya Kaneko, Yoshifumi Ohchi, Yuhki Sato, Norihisa Yasuda, Koji Goto, Takaaki Kitano, Hiroki Itoh
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/27a65936ad8a48dda497e5e8845681d8
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