Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge

Eosinophils are important mediators of allergic responses, but how they are recruited to the inflamed site is still unclear. Here the authors show that CD103+ cDC1 cells secrete CCL17 and CCL22 for eosinophil recruitment, with this process promoted by CD24−CD11b+ DC2s in the early phase but suppress...

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Autores principales:	Shuying Yi, Jing Zhai, Rui Niu, Guangming Zhu, Meixiang Wang, Jianguo Liu, Hua Huang, Yaping Wang, Xiuli Jing, Li Kang, Wengang Song, Yufang Shi, Hua Tang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/27a6b8c71a2d4b0fbb48437037090399
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spelling	oai:doaj.org-article:27a6b8c71a2d4b0fbb484370370903992021-12-02T17:31:44ZEosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge10.1038/s41467-018-06316-92041-1723https://doaj.org/article/27a6b8c71a2d4b0fbb484370370903992018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06316-9https://doaj.org/toc/2041-1723Eosinophils are important mediators of allergic responses, but how they are recruited to the inflamed site is still unclear. Here the authors show that CD103+ cDC1 cells secrete CCL17 and CCL22 for eosinophil recruitment, with this process promoted by CD24−CD11b+ DC2s in the early phase but suppressed by CD24+ cDC2s in the late phase.Shuying YiJing ZhaiRui NiuGuangming ZhuMeixiang WangJianguo LiuHua HuangYaping WangXiuli JingLi KangWengang SongYufang ShiHua TangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shuying Yi Jing Zhai Rui Niu Guangming Zhu Meixiang Wang Jianguo Liu Hua Huang Yaping Wang Xiuli Jing Li Kang Wengang Song Yufang Shi Hua Tang Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge
description	Eosinophils are important mediators of allergic responses, but how they are recruited to the inflamed site is still unclear. Here the authors show that CD103+ cDC1 cells secrete CCL17 and CCL22 for eosinophil recruitment, with this process promoted by CD24−CD11b+ DC2s in the early phase but suppressed by CD24+ cDC2s in the late phase.
format	article
author	Shuying Yi Jing Zhai Rui Niu Guangming Zhu Meixiang Wang Jianguo Liu Hua Huang Yaping Wang Xiuli Jing Li Kang Wengang Song Yufang Shi Hua Tang
author_facet	Shuying Yi Jing Zhai Rui Niu Guangming Zhu Meixiang Wang Jianguo Liu Hua Huang Yaping Wang Xiuli Jing Li Kang Wengang Song Yufang Shi Hua Tang
author_sort	Shuying Yi
title	Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge
title_short	Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge
title_full	Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge
title_fullStr	Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge
title_full_unstemmed	Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge
title_sort	eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/27a6b8c71a2d4b0fbb48437037090399
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_version_	1718380478296227840

Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge

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