Bullous pemphigoid induced by Hijama therapy (cupping)

Bullous pemphigoid (BP) is described as a subepidermal blistering disorder, which is commonly reported among the elderly, particularly those older than 60 years of age. In this report, we present the case of a 41-year-old female patient with BP lesions that were initially detected at the site of Hi...

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Autores principales: Arghavan Azizpour, Maryam Nasimi, Safoura Shakoei, Fariba Mohammadi, Arsalan Azizpour
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Lenguaje:EN
Publicado: Mattioli1885 2018
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Acceso en línea:https://doaj.org/article/27a8f9b6bc4e46129d218cc4d0152379
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spelling oai:doaj.org-article:27a8f9b6bc4e46129d218cc4d01523792021-11-17T08:30:06ZBullous pemphigoid induced by Hijama therapy (cupping)2160-9381https://doaj.org/article/27a8f9b6bc4e46129d218cc4d01523792018-07-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/424https://doaj.org/toc/2160-9381 Bullous pemphigoid (BP) is described as a subepidermal blistering disorder, which is commonly reported among the elderly, particularly those older than 60 years of age. In this report, we present the case of a 41-year-old female patient with BP lesions that were initially detected at the site of Hijama therapy with a subsequent generalized spread. Punch biopsy from the lesions and perilesional direct immunofluorescence (DIF) demonstrated features of BP. The anti-BP180 level was 178 RU/mL, and the anti-BP230 level was negative. BP antigens at the site of Hijama caused an antibody response, which led to widespread blistering over the trunk due to epitope spreading. In a comprehensive review of the literature, a total of 22 BP patients with lesions due to physical trauma were studied, and clinical, immunological, and epidemiological information was gathered. This article is the first report on the occurrence of BP induced by Hijama therapy. Arghavan AzizpourMaryam NasimiSafoura ShakoeiFariba MohammadiArsalan AzizpourMattioli1885articlebullous pemphigoidHijamatrigger factortraumaDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 8, Iss 3 (2018)
institution DOAJ
collection DOAJ
language EN
topic bullous pemphigoid
Hijama
trigger factor
trauma
Dermatology
RL1-803
spellingShingle bullous pemphigoid
Hijama
trigger factor
trauma
Dermatology
RL1-803
Arghavan Azizpour
Maryam Nasimi
Safoura Shakoei
Fariba Mohammadi
Arsalan Azizpour
Bullous pemphigoid induced by Hijama therapy (cupping)
description Bullous pemphigoid (BP) is described as a subepidermal blistering disorder, which is commonly reported among the elderly, particularly those older than 60 years of age. In this report, we present the case of a 41-year-old female patient with BP lesions that were initially detected at the site of Hijama therapy with a subsequent generalized spread. Punch biopsy from the lesions and perilesional direct immunofluorescence (DIF) demonstrated features of BP. The anti-BP180 level was 178 RU/mL, and the anti-BP230 level was negative. BP antigens at the site of Hijama caused an antibody response, which led to widespread blistering over the trunk due to epitope spreading. In a comprehensive review of the literature, a total of 22 BP patients with lesions due to physical trauma were studied, and clinical, immunological, and epidemiological information was gathered. This article is the first report on the occurrence of BP induced by Hijama therapy.
format article
author Arghavan Azizpour
Maryam Nasimi
Safoura Shakoei
Fariba Mohammadi
Arsalan Azizpour
author_facet Arghavan Azizpour
Maryam Nasimi
Safoura Shakoei
Fariba Mohammadi
Arsalan Azizpour
author_sort Arghavan Azizpour
title Bullous pemphigoid induced by Hijama therapy (cupping)
title_short Bullous pemphigoid induced by Hijama therapy (cupping)
title_full Bullous pemphigoid induced by Hijama therapy (cupping)
title_fullStr Bullous pemphigoid induced by Hijama therapy (cupping)
title_full_unstemmed Bullous pemphigoid induced by Hijama therapy (cupping)
title_sort bullous pemphigoid induced by hijama therapy (cupping)
publisher Mattioli1885
publishDate 2018
url https://doaj.org/article/27a8f9b6bc4e46129d218cc4d0152379
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AT maryamnasimi bullouspemphigoidinducedbyhijamatherapycupping
AT safourashakoei bullouspemphigoidinducedbyhijamatherapycupping
AT faribamohammadi bullouspemphigoidinducedbyhijamatherapycupping
AT arsalanazizpour bullouspemphigoidinducedbyhijamatherapycupping
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