EFFECTS OF CHRONOLOGICAL AGEING ON EPIDERMAL THICKNESS OF HUMAN SKIN IN DIFFERENT AGE GROUPS

Objective: To compare the age related changes in thickness of skin epidermis in different age groups in the Pakistani population. Study Design: Cross sectional study. Place and Duration of Study: The study was conducted at Army Medical College, Rawalpindi, for a period of five months, from...

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Autores principales:	Ayesha Baqar, Shazia Muazam, Saadia Rashid, Khadija Qamar
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2018
Materias:	ageing epidermis Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/27b96dc2b49a4dba8e7daa981917d283
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spelling	oai:doaj.org-article:27b96dc2b49a4dba8e7daa981917d2832021-11-26T03:19:41ZEFFECTS OF CHRONOLOGICAL AGEING ON EPIDERMAL THICKNESS OF HUMAN SKIN IN DIFFERENT AGE GROUPS0030-96482411-8842https://doaj.org/article/27b96dc2b49a4dba8e7daa981917d2832018-12-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2559/2097https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare the age related changes in thickness of skin epidermis in different age groups in the Pakistani population. Study Design: Cross sectional study. Place and Duration of Study: The study was conducted at Army Medical College, Rawalpindi, for a period of five months, from Jul 2010 to Nov 2010. All protocols were approved by the Ethical committee of centre for research in experimental and applied medicine (CREAM), Army Medical College, Rawalpindi. Patients and Methods: In this study, 60 volunteers of both genders, fulfilling the inclusion criteria, were divided according to age, into three equal groups, 18-29 years, 30-49 years, and more than 50 years, Groups A, B and C respectively. All study participants gave written consent before their inclusion in the study Four-mm full-thickness punch biopsy of sun protected upper arm skin of left side was obtained from each individual after administration of local anesthetic injection. The samples were stained with Haematoxylin and Eosin for histomorphological study and comparison of epidermal thickness was done between the three groups. In each section, the epidermal thickness was measured at three points to determine maximum thickness, under 10X objective. Mean of three readings of each sample was taken. Then, mean of each group was taken and that of the three groups was compared to determine the presence or absence of epidermal atrophy. Results: There was no appreciable difference in epidermal thickness between the three groups. Mean of group A was 144.833 μm, that of group-B was 142.833 μm and the mean value of group C was 125.5 μm. Conclusion: It was concluded that, although human skin markedly deteriorates visibly with age, the epidermal thickness remains constant.Ayesha BaqarShazia MuazamSaadia RashidKhadija QamarArmy Medical College RawalpindiarticleageingepidermisMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 6, Pp 1619-1624 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	ageing epidermis Medicine R Medicine (General) R5-920
spellingShingle	ageing epidermis Medicine R Medicine (General) R5-920 Ayesha Baqar Shazia Muazam Saadia Rashid Khadija Qamar EFFECTS OF CHRONOLOGICAL AGEING ON EPIDERMAL THICKNESS OF HUMAN SKIN IN DIFFERENT AGE GROUPS
description	Objective: To compare the age related changes in thickness of skin epidermis in different age groups in the Pakistani population. Study Design: Cross sectional study. Place and Duration of Study: The study was conducted at Army Medical College, Rawalpindi, for a period of five months, from Jul 2010 to Nov 2010. All protocols were approved by the Ethical committee of centre for research in experimental and applied medicine (CREAM), Army Medical College, Rawalpindi. Patients and Methods: In this study, 60 volunteers of both genders, fulfilling the inclusion criteria, were divided according to age, into three equal groups, 18-29 years, 30-49 years, and more than 50 years, Groups A, B and C respectively. All study participants gave written consent before their inclusion in the study Four-mm full-thickness punch biopsy of sun protected upper arm skin of left side was obtained from each individual after administration of local anesthetic injection. The samples were stained with Haematoxylin and Eosin for histomorphological study and comparison of epidermal thickness was done between the three groups. In each section, the epidermal thickness was measured at three points to determine maximum thickness, under 10X objective. Mean of three readings of each sample was taken. Then, mean of each group was taken and that of the three groups was compared to determine the presence or absence of epidermal atrophy. Results: There was no appreciable difference in epidermal thickness between the three groups. Mean of group A was 144.833 μm, that of group-B was 142.833 μm and the mean value of group C was 125.5 μm. Conclusion: It was concluded that, although human skin markedly deteriorates visibly with age, the epidermal thickness remains constant.
format	article
author	Ayesha Baqar Shazia Muazam Saadia Rashid Khadija Qamar
author_facet	Ayesha Baqar Shazia Muazam Saadia Rashid Khadija Qamar
author_sort	Ayesha Baqar
title	EFFECTS OF CHRONOLOGICAL AGEING ON EPIDERMAL THICKNESS OF HUMAN SKIN IN DIFFERENT AGE GROUPS
title_short	EFFECTS OF CHRONOLOGICAL AGEING ON EPIDERMAL THICKNESS OF HUMAN SKIN IN DIFFERENT AGE GROUPS
title_full	EFFECTS OF CHRONOLOGICAL AGEING ON EPIDERMAL THICKNESS OF HUMAN SKIN IN DIFFERENT AGE GROUPS
title_fullStr	EFFECTS OF CHRONOLOGICAL AGEING ON EPIDERMAL THICKNESS OF HUMAN SKIN IN DIFFERENT AGE GROUPS
title_full_unstemmed	EFFECTS OF CHRONOLOGICAL AGEING ON EPIDERMAL THICKNESS OF HUMAN SKIN IN DIFFERENT AGE GROUPS
title_sort	effects of chronological ageing on epidermal thickness of human skin in different age groups
publisher	Army Medical College Rawalpindi
publishDate	2018
url	https://doaj.org/article/27b96dc2b49a4dba8e7daa981917d283
work_keys_str_mv	AT ayeshabaqar effectsofchronologicalageingonepidermalthicknessofhumanskinindifferentagegroups AT shaziamuazam effectsofchronologicalageingonepidermalthicknessofhumanskinindifferentagegroups AT saadiarashid effectsofchronologicalageingonepidermalthicknessofhumanskinindifferentagegroups AT khadijaqamar effectsofchronologicalageingonepidermalthicknessofhumanskinindifferentagegroups
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EFFECTS OF CHRONOLOGICAL AGEING ON EPIDERMAL THICKNESS OF HUMAN SKIN IN DIFFERENT AGE GROUPS

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