Comprehensive characterization of RAS mutations in colon and rectal cancers in old and young patients
Activating oncogenic mutations in KRAS and NRAS are common in colorectal cancer, which is a heterogenous disease. Here, the authors show that the RAS mutation spectrum is markedly different between colon and rectal cancer, and also different based on age of diagnosis and microsatellite instability.
Guardado en:
Autores principales: | Ilya G. Serebriiskii, Caitlin Connelly, Garrett Frampton, Justin Newberg, Matthew Cooke, Vince Miller, Siraj Ali, Jeffrey S. Ross, Elizabeth Handorf, Sanjeevani Arora, Christopher Lieu, Erica A. Golemis, Joshua E. Meyer |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/27bc5c9b4b90416a81f526fbc7b0c8ee |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis
por: Suraj Peri, et al.
Publicado: (2017) -
Taiwan Society of Colon and Rectal Surgeons Consensus on mCRC Treatment
por: Hong-Hwa Chen, et al.
Publicado: (2021) -
Autophagy Flux Correlates with Upregulation of AKT-1 in RAS Mutated Colon Cancer Cells
por: Hamid Behrouj, et al.
Publicado: (2021) -
Prolonged rectal shedding of SARS-CoV-2 in a 22-day-old-neonate: a case report
por: Julie Niemann Holm-Jacobsen, et al.
Publicado: (2021) -
Prevalence of pathogenic variants in DNA damage response and repair genes in patients undergoing cancer risk assessment and reporting a personal history of early-onset renal cancer
por: Tiffiney R. Hartman, et al.
Publicado: (2020)