Human amnion-derived mesenchymal stem cells attenuate xenogeneic graft-versus-host disease by preventing T cell activation and proliferation

Human amnion-derived mesenchymal stem cells attenuate xenogeneic graft-versus-host disease by preventing T cell activation and proliferation

Abstract Acute graft-versus-host disease (GVHD) is characterized by severe tissue damage that is a life-threatening complication of allogeneic hematopoietic stem cell transplantation. Due to their immunosuppressive properties, mesenchymal stem cells (MSC) have been increasingly examined for the trea...

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Bibliographic Details
Main Authors: Yoshiyuki Tago, Chiho Kobayashi, Mineko Ogura, Jutaro Wada, Sho Yamaguchi, Takashi Yamaguchi, Masahiro Hayashi, Tomoyuki Nakaishi, Hiroshi Kubo, Yasuyoshi Ueda
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/27be7c097a5e4194815dd4fc9c8dfa63
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