A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation

In plants, RNA-directed DNA methylation (RdDM) is a de novo DNA methylation pathway that is responsible for transcriptional silencing of repetitive elements. Here, the authors characterized a new RdDM factor, RDM15, and show that it is required for RdDM-dependent DNA methylation and siRNA accumulati...

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Autores principales: Qingfeng Niu, Zhe Song, Kai Tang, Lixian Chen, Lisi Wang, Ting Ban, Zhongxin Guo, Chanhong Kim, Heng Zhang, Cheng-Guo Duan, Huiming Zhang, Jian-Kang Zhu, Jiamu Du, Zhaobo Lang
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/27e47ff79fc54054b5f8e15e06ee5e28
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spelling oai:doaj.org-article:27e47ff79fc54054b5f8e15e06ee5e282021-12-02T17:47:14ZA histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation10.1038/s41467-021-23637-42041-1723https://doaj.org/article/27e47ff79fc54054b5f8e15e06ee5e282021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23637-4https://doaj.org/toc/2041-1723In plants, RNA-directed DNA methylation (RdDM) is a de novo DNA methylation pathway that is responsible for transcriptional silencing of repetitive elements. Here, the authors characterized a new RdDM factor, RDM15, and show that it is required for RdDM-dependent DNA methylation and siRNA accumulation at a subset of RdDM target loci.Qingfeng NiuZhe SongKai TangLixian ChenLisi WangTing BanZhongxin GuoChanhong KimHeng ZhangCheng-Guo DuanHuiming ZhangJian-Kang ZhuJiamu DuZhaobo LangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qingfeng Niu
Zhe Song
Kai Tang
Lixian Chen
Lisi Wang
Ting Ban
Zhongxin Guo
Chanhong Kim
Heng Zhang
Cheng-Guo Duan
Huiming Zhang
Jian-Kang Zhu
Jiamu Du
Zhaobo Lang
A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation
description In plants, RNA-directed DNA methylation (RdDM) is a de novo DNA methylation pathway that is responsible for transcriptional silencing of repetitive elements. Here, the authors characterized a new RdDM factor, RDM15, and show that it is required for RdDM-dependent DNA methylation and siRNA accumulation at a subset of RdDM target loci.
format article
author Qingfeng Niu
Zhe Song
Kai Tang
Lixian Chen
Lisi Wang
Ting Ban
Zhongxin Guo
Chanhong Kim
Heng Zhang
Cheng-Guo Duan
Huiming Zhang
Jian-Kang Zhu
Jiamu Du
Zhaobo Lang
author_facet Qingfeng Niu
Zhe Song
Kai Tang
Lixian Chen
Lisi Wang
Ting Ban
Zhongxin Guo
Chanhong Kim
Heng Zhang
Cheng-Guo Duan
Huiming Zhang
Jian-Kang Zhu
Jiamu Du
Zhaobo Lang
author_sort Qingfeng Niu
title A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation
title_short A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation
title_full A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation
title_fullStr A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation
title_full_unstemmed A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation
title_sort histone h3k4me1-specific binding protein is required for sirna accumulation and dna methylation at a subset of loci targeted by rna-directed dna methylation
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/27e47ff79fc54054b5f8e15e06ee5e28
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