Crystal structure of an integron gene cassette-associated protein from Vibrio cholerae identifies a cationic drug-binding module.

Crystal structure of an integron gene cassette-associated protein from Vibrio cholerae identifies a cationic drug-binding module.

<h4>Background</h4>The direct isolation of integron gene cassettes from cultivated and environmental microbial sources allows an assessment of the impact of the integron/gene cassette system on the emergence of new phenotypes, such as drug resistance or virulence. A structural approach i...

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Main Authors: Chandrika N Deshpande, Stephen J Harrop, Yan Boucher, Karl A Hassan, Rosa Di Leo, Xiaohui Xu, Hong Cui, Alexei Savchenko, Changsoo Chang, Maurizio Labbate, Ian T Paulsen, H W Stokes, Paul M G Curmi, Bridget C Mabbutt
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/27ee1f1cef2741cfa8f07a1d7d7df220
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