IRF3 prevents colorectal tumorigenesis via inhibiting the nuclear translocation of β-catenin
The alternative mechanisms of innate immunity in tumorigenesis of colorectal cancers are unclear. Here, the authors report a non-canonical function of IRF3, a mediator of innate immune signalling, in the suppression of colorectal tumorigenesis and this is via the inhibition of Wnt/β-catenin pathway....
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
|
| Subjects: | |
| Online Access: | https://doaj.org/article/27fd64e8f5954df280d638580267b400 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|