Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation
Caveolae are spherical nanodomains of the plasma membrane generated by assembly of caveolin and cavin proteins. Here, the authors show that fuzzy electrostatic interactions between caveolin-1 and Cavin1 proteins, combined with membrane lipid interactions, are required to generate membrane curvature...
Guardado en:
Autores principales: | Vikas A. Tillu, James Rae, Ya Gao, Nicholas Ariotti, Matthias Floetenmeyer, Oleksiy Kovtun, Kerrie-Ann McMahon, Natasha Chaudhary, Robert G. Parton, Brett M. Collins |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2807bb40181f4244bd067fd1cb562ab3 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis
por: Kerrie-Ann McMahon, et al.
Publicado: (2019) -
ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1
por: Tomoya Yamaguchi, et al.
Publicado: (2016) -
Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
por: Jamie J. L. Williams, et al.
Publicado: (2018) -
Co-regulation of cell polarization and migration by caveolar proteins PTRF/Cavin-1 and caveolin-1.
por: Michelle M Hill, et al.
Publicado: (2012) -
Cavin1; a regulator of lung function and macrophage phenotype.
por: Praveen Govender, et al.
Publicado: (2013)