Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b

Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) is important for invasion of reticulocytes and PvRBP2b antibodies correlate with protection. Here, Chan et al. isolate and characterize anti-PvRBP2b human monoclonal antibodies and describe mechanisms by which these antibodies inhibit invasi...

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Autores principales: Li-Jin Chan, Anugraha Gandhirajan, Lenore L. Carias, Melanie H. Dietrich, Oscar Vadas, Remy Visentin, Camila T. França, Sebastien Menant, Dominique Soldati-Favre, Ivo Mueller, Christopher L. King, Wai-Hong Tham
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/281a04da1cad4cea92f1a8e4257187e0
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spelling oai:doaj.org-article:281a04da1cad4cea92f1a8e4257187e02021-12-02T13:33:02ZNaturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b10.1038/s41467-021-21811-22041-1723https://doaj.org/article/281a04da1cad4cea92f1a8e4257187e02021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21811-2https://doaj.org/toc/2041-1723Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) is important for invasion of reticulocytes and PvRBP2b antibodies correlate with protection. Here, Chan et al. isolate and characterize anti-PvRBP2b human monoclonal antibodies and describe mechanisms by which these antibodies inhibit invasion.Li-Jin ChanAnugraha GandhirajanLenore L. CariasMelanie H. DietrichOscar VadasRemy VisentinCamila T. FrançaSebastien MenantDominique Soldati-FavreIvo MuellerChristopher L. KingWai-Hong ThamNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Li-Jin Chan
Anugraha Gandhirajan
Lenore L. Carias
Melanie H. Dietrich
Oscar Vadas
Remy Visentin
Camila T. França
Sebastien Menant
Dominique Soldati-Favre
Ivo Mueller
Christopher L. King
Wai-Hong Tham
Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b
description Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) is important for invasion of reticulocytes and PvRBP2b antibodies correlate with protection. Here, Chan et al. isolate and characterize anti-PvRBP2b human monoclonal antibodies and describe mechanisms by which these antibodies inhibit invasion.
format article
author Li-Jin Chan
Anugraha Gandhirajan
Lenore L. Carias
Melanie H. Dietrich
Oscar Vadas
Remy Visentin
Camila T. França
Sebastien Menant
Dominique Soldati-Favre
Ivo Mueller
Christopher L. King
Wai-Hong Tham
author_facet Li-Jin Chan
Anugraha Gandhirajan
Lenore L. Carias
Melanie H. Dietrich
Oscar Vadas
Remy Visentin
Camila T. França
Sebastien Menant
Dominique Soldati-Favre
Ivo Mueller
Christopher L. King
Wai-Hong Tham
author_sort Li-Jin Chan
title Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b
title_short Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b
title_full Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b
title_fullStr Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b
title_full_unstemmed Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b
title_sort naturally acquired blocking human monoclonal antibodies to plasmodium vivax reticulocyte binding protein 2b
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/281a04da1cad4cea92f1a8e4257187e0
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