Cryotherapy versus CO2 laser in the treatment of plantar warts: a randomized controlled trial

Background: Warts are one of the most common infections in humans. Plantar warts are a subtype of non-genital warts, and several procedures and topical treatments have been used in its treatment. Cryotherapy is one of the most popular modalities, but it is time-consuming and remission rates vary in...

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Autores principales:	Nahid Hemmatian Boroujeni, Farhad Handjani
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2018
Materias:	cryotherapy dermatologic surgery warts plantar warts randomized controlled trial Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/282f6af7e740432d8b9f20999a7bcc4b
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spelling	oai:doaj.org-article:282f6af7e740432d8b9f20999a7bcc4b2021-11-17T08:30:00ZCryotherapy versus CO2 laser in the treatment of plantar warts: a randomized controlled trial2160-9381https://doaj.org/article/282f6af7e740432d8b9f20999a7bcc4b2018-07-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/481https://doaj.org/toc/2160-9381 Background: Warts are one of the most common infections in humans. Plantar warts are a subtype of non-genital warts, and several procedures and topical treatments have been used in its treatment. Cryotherapy is one of the most popular modalities, but it is time-consuming and remission rates vary in different studies. CO2 laser was the first laser used for treating warts. To date, no clinical trial has been done to compare CO2 laser with cryotherapy in the treatment of plantar warts. Patients and Methods: This randomized controlled trial was performed in order to compare the efficacy and number of sessions needed to treat plantar warts in 60 patients who had received no previous treatment in the previous 3 months. They were randomly allocated to the cryotherapy or CO2 laser group. The number of sessions needed for response and the recurrence rate after a 3-month follow-up was compared in the 2 groups. Results: Sixty patients with plantar warts were randomly allocated to either the CO2 laser or cryotherapy groups. Median age was 25 (range=18-53) and 27 (range= 18-75) years in the cryotherapy group and CO2 laser groups, respectively. Both groups were matched for age and sex (56% male and 44% female in the cryotherapy group and 34% male and 66% female in the CO2 laser group). The median number of sessions needed for complete resolution of the warts in the CO2 laser and cryotherapy groups were 1 (range=1-2) and 3 (range=1-12), respectively. The difference in the number of sessions was statistically significant between the 2 groups (P-value≤0.001). Recurrence rates after a 3-month follow-up was not statistically significant (P-value= 0.069). Conclusion: The number of sessions needed to treat plantar warts was less using CO2 laser than cryotherapy; therefore, this modality can be a good addition to the already existing anti-wart armamentarium. Nahid Hemmatian BoroujeniFarhad HandjaniMattioli1885articlecryotherapydermatologic surgerywartsplantar wartsrandomized controlled trialDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 8, Iss 3 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	cryotherapy dermatologic surgery warts plantar warts randomized controlled trial Dermatology RL1-803
spellingShingle	cryotherapy dermatologic surgery warts plantar warts randomized controlled trial Dermatology RL1-803 Nahid Hemmatian Boroujeni Farhad Handjani Cryotherapy versus CO2 laser in the treatment of plantar warts: a randomized controlled trial
description	Background: Warts are one of the most common infections in humans. Plantar warts are a subtype of non-genital warts, and several procedures and topical treatments have been used in its treatment. Cryotherapy is one of the most popular modalities, but it is time-consuming and remission rates vary in different studies. CO2 laser was the first laser used for treating warts. To date, no clinical trial has been done to compare CO2 laser with cryotherapy in the treatment of plantar warts. Patients and Methods: This randomized controlled trial was performed in order to compare the efficacy and number of sessions needed to treat plantar warts in 60 patients who had received no previous treatment in the previous 3 months. They were randomly allocated to the cryotherapy or CO2 laser group. The number of sessions needed for response and the recurrence rate after a 3-month follow-up was compared in the 2 groups. Results: Sixty patients with plantar warts were randomly allocated to either the CO2 laser or cryotherapy groups. Median age was 25 (range=18-53) and 27 (range= 18-75) years in the cryotherapy group and CO2 laser groups, respectively. Both groups were matched for age and sex (56% male and 44% female in the cryotherapy group and 34% male and 66% female in the CO2 laser group). The median number of sessions needed for complete resolution of the warts in the CO2 laser and cryotherapy groups were 1 (range=1-2) and 3 (range=1-12), respectively. The difference in the number of sessions was statistically significant between the 2 groups (P-value≤0.001). Recurrence rates after a 3-month follow-up was not statistically significant (P-value= 0.069). Conclusion: The number of sessions needed to treat plantar warts was less using CO2 laser than cryotherapy; therefore, this modality can be a good addition to the already existing anti-wart armamentarium.
format	article
author	Nahid Hemmatian Boroujeni Farhad Handjani
author_facet	Nahid Hemmatian Boroujeni Farhad Handjani
author_sort	Nahid Hemmatian Boroujeni
title	Cryotherapy versus CO2 laser in the treatment of plantar warts: a randomized controlled trial
title_short	Cryotherapy versus CO2 laser in the treatment of plantar warts: a randomized controlled trial
title_full	Cryotherapy versus CO2 laser in the treatment of plantar warts: a randomized controlled trial
title_fullStr	Cryotherapy versus CO2 laser in the treatment of plantar warts: a randomized controlled trial
title_full_unstemmed	Cryotherapy versus CO2 laser in the treatment of plantar warts: a randomized controlled trial
title_sort	cryotherapy versus co2 laser in the treatment of plantar warts: a randomized controlled trial
publisher	Mattioli1885
publishDate	2018
url	https://doaj.org/article/282f6af7e740432d8b9f20999a7bcc4b
work_keys_str_mv	AT nahidhemmatianboroujeni cryotherapyversusco2laserinthetreatmentofplantarwartsarandomizedcontrolledtrial AT farhadhandjani cryotherapyversusco2laserinthetreatmentofplantarwartsarandomizedcontrolledtrial
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Cryotherapy versus CO2 laser in the treatment of plantar warts: a randomized controlled trial

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