Detection of spacer precursors formed in vivo during primed CRISPR adaptation

Primed adaptation in the CRISPR-Cas system helps recognition of previously encountered sequence elements and promotes the formation of new memories. Here the authors characterized spacer precursors of type I-E and type I-F CRISPR-Cas system using in vivo models.

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Autores principales: Anna A. Shiriaeva, Ekaterina Savitskaya, Kirill A. Datsenko, Irina O. Vvedenskaya, Iana Fedorova, Natalia Morozova, Anastasia Metlitskaya, Anton Sabantsev, Bryce E. Nickels, Konstantin Severinov, Ekaterina Semenova
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2843ec11149841ccb9221461a5c00330
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spelling oai:doaj.org-article:2843ec11149841ccb9221461a5c003302021-12-02T17:02:02ZDetection of spacer precursors formed in vivo during primed CRISPR adaptation10.1038/s41467-019-12417-w2041-1723https://doaj.org/article/2843ec11149841ccb9221461a5c003302019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12417-whttps://doaj.org/toc/2041-1723Primed adaptation in the CRISPR-Cas system helps recognition of previously encountered sequence elements and promotes the formation of new memories. Here the authors characterized spacer precursors of type I-E and type I-F CRISPR-Cas system using in vivo models.Anna A. ShiriaevaEkaterina SavitskayaKirill A. DatsenkoIrina O. VvedenskayaIana FedorovaNatalia MorozovaAnastasia MetlitskayaAnton SabantsevBryce E. NickelsKonstantin SeverinovEkaterina SemenovaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anna A. Shiriaeva
Ekaterina Savitskaya
Kirill A. Datsenko
Irina O. Vvedenskaya
Iana Fedorova
Natalia Morozova
Anastasia Metlitskaya
Anton Sabantsev
Bryce E. Nickels
Konstantin Severinov
Ekaterina Semenova
Detection of spacer precursors formed in vivo during primed CRISPR adaptation
description Primed adaptation in the CRISPR-Cas system helps recognition of previously encountered sequence elements and promotes the formation of new memories. Here the authors characterized spacer precursors of type I-E and type I-F CRISPR-Cas system using in vivo models.
format article
author Anna A. Shiriaeva
Ekaterina Savitskaya
Kirill A. Datsenko
Irina O. Vvedenskaya
Iana Fedorova
Natalia Morozova
Anastasia Metlitskaya
Anton Sabantsev
Bryce E. Nickels
Konstantin Severinov
Ekaterina Semenova
author_facet Anna A. Shiriaeva
Ekaterina Savitskaya
Kirill A. Datsenko
Irina O. Vvedenskaya
Iana Fedorova
Natalia Morozova
Anastasia Metlitskaya
Anton Sabantsev
Bryce E. Nickels
Konstantin Severinov
Ekaterina Semenova
author_sort Anna A. Shiriaeva
title Detection of spacer precursors formed in vivo during primed CRISPR adaptation
title_short Detection of spacer precursors formed in vivo during primed CRISPR adaptation
title_full Detection of spacer precursors formed in vivo during primed CRISPR adaptation
title_fullStr Detection of spacer precursors formed in vivo during primed CRISPR adaptation
title_full_unstemmed Detection of spacer precursors formed in vivo during primed CRISPR adaptation
title_sort detection of spacer precursors formed in vivo during primed crispr adaptation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/2843ec11149841ccb9221461a5c00330
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