Nationwide vitamin D status in older Brazilian adults and its determinants: The Brazilian Longitudinal Study of Aging (ELSI)

Abstract Little is known about vitamin D status in older adults in South America, where exposures to ultra-violet radiation are high. We examined the distribution of serum 25-hydroxyvitamin D (25OHD) concentration and its determinants in a nationally representative sample of Brazilians aged 50 years...

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Autores principales:	Maria Fernanda Lima-Costa, Juliana V. M. Mambrini, Paulo R. Borges de Souza-Junior, Fabíola Bof de Andrade, Sérgio V. Peixoto, Clarissa M. Vidigal, Cesar de Oliveira, Pedro G. Vidigal
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/28467d8411ad4df094e88ff572b4a773
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spelling	oai:doaj.org-article:28467d8411ad4df094e88ff572b4a7732021-12-02T18:50:56ZNationwide vitamin D status in older Brazilian adults and its determinants: The Brazilian Longitudinal Study of Aging (ELSI)10.1038/s41598-020-70329-y2045-2322https://doaj.org/article/28467d8411ad4df094e88ff572b4a7732020-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-70329-yhttps://doaj.org/toc/2045-2322Abstract Little is known about vitamin D status in older adults in South America, where exposures to ultra-violet radiation are high. We examined the distribution of serum 25-hydroxyvitamin D (25OHD) concentration and its determinants in a nationally representative sample of Brazilians aged 50 years and older. Explanatory variables included environment and individuals’ characteristics from the ELSI baseline survey (2015–16). Among the 2,264 participants (mean age = 62.6 years), the geometric mean of 25OHD concentration was 66.8 nmol/L. The prevalence of vitamin D deficiency (< 30 nmol/L) and insufficiency (< 50 nmol/L) were 1.7% (95% CI 1.0, 2.8) and 16% (95% CI 12, 20), respectively. Mean concentrations were lower in those geographical regions situated at lower latitudes. Those at the oldest age, women, self-classified as Black and Brown, living in urban areas and current smokers were more likely to have vitamin D insufficiency, independent of each other and other relevant factors. In contrast, individuals who eat fish regularly were considerably less likely to present lower concentration. Based on these findings it is possible to estimate that about 875,000 older Brazilians have vitamin D deficiency and 7.5 million its insufficiency.Maria Fernanda Lima-CostaJuliana V. M. MambriniPaulo R. Borges de Souza-JuniorFabíola Bof de AndradeSérgio V. PeixotoClarissa M. VidigalCesar de OliveiraPedro G. VidigalNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Maria Fernanda Lima-Costa Juliana V. M. Mambrini Paulo R. Borges de Souza-Junior Fabíola Bof de Andrade Sérgio V. Peixoto Clarissa M. Vidigal Cesar de Oliveira Pedro G. Vidigal Nationwide vitamin D status in older Brazilian adults and its determinants: The Brazilian Longitudinal Study of Aging (ELSI)
description	Abstract Little is known about vitamin D status in older adults in South America, where exposures to ultra-violet radiation are high. We examined the distribution of serum 25-hydroxyvitamin D (25OHD) concentration and its determinants in a nationally representative sample of Brazilians aged 50 years and older. Explanatory variables included environment and individuals’ characteristics from the ELSI baseline survey (2015–16). Among the 2,264 participants (mean age = 62.6 years), the geometric mean of 25OHD concentration was 66.8 nmol/L. The prevalence of vitamin D deficiency (< 30 nmol/L) and insufficiency (< 50 nmol/L) were 1.7% (95% CI 1.0, 2.8) and 16% (95% CI 12, 20), respectively. Mean concentrations were lower in those geographical regions situated at lower latitudes. Those at the oldest age, women, self-classified as Black and Brown, living in urban areas and current smokers were more likely to have vitamin D insufficiency, independent of each other and other relevant factors. In contrast, individuals who eat fish regularly were considerably less likely to present lower concentration. Based on these findings it is possible to estimate that about 875,000 older Brazilians have vitamin D deficiency and 7.5 million its insufficiency.
format	article
author	Maria Fernanda Lima-Costa Juliana V. M. Mambrini Paulo R. Borges de Souza-Junior Fabíola Bof de Andrade Sérgio V. Peixoto Clarissa M. Vidigal Cesar de Oliveira Pedro G. Vidigal
author_facet	Maria Fernanda Lima-Costa Juliana V. M. Mambrini Paulo R. Borges de Souza-Junior Fabíola Bof de Andrade Sérgio V. Peixoto Clarissa M. Vidigal Cesar de Oliveira Pedro G. Vidigal
author_sort	Maria Fernanda Lima-Costa
title	Nationwide vitamin D status in older Brazilian adults and its determinants: The Brazilian Longitudinal Study of Aging (ELSI)
title_short	Nationwide vitamin D status in older Brazilian adults and its determinants: The Brazilian Longitudinal Study of Aging (ELSI)
title_full	Nationwide vitamin D status in older Brazilian adults and its determinants: The Brazilian Longitudinal Study of Aging (ELSI)
title_fullStr	Nationwide vitamin D status in older Brazilian adults and its determinants: The Brazilian Longitudinal Study of Aging (ELSI)
title_full_unstemmed	Nationwide vitamin D status in older Brazilian adults and its determinants: The Brazilian Longitudinal Study of Aging (ELSI)
title_sort	nationwide vitamin d status in older brazilian adults and its determinants: the brazilian longitudinal study of aging (elsi)
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/28467d8411ad4df094e88ff572b4a773
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Nationwide vitamin D status in older Brazilian adults and its determinants: The Brazilian Longitudinal Study of Aging (ELSI)

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