Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC
Lung cancer is the leading cause of cancer-related deaths across the world, of which non-small cell lung cancer (NSCLC) accounts for 85%, and more than 50% of NSCLC patients were diagnosed with distant metastasis. The comprehensive treatment of NSCLC includes surgery, radiotherapy, chemotherapy, tar...
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Magazine House of Cancer Research on Prevention and Treatment
2021
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oai:doaj.org-article:285b3c127ca447da9782f43b0837486a2021-11-05T02:22:52ZClinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC1000-857810.3971/j.issn.1000-8578.2021.21.0382https://doaj.org/article/285b3c127ca447da9782f43b0837486a2021-10-01T00:00:00Zhttp://html.rhhz.net/ZLFZYJ/html/8578.2021.21.0382.htmhttps://doaj.org/toc/1000-8578Lung cancer is the leading cause of cancer-related deaths across the world, of which non-small cell lung cancer (NSCLC) accounts for 85%, and more than 50% of NSCLC patients were diagnosed with distant metastasis. The comprehensive treatment of NSCLC includes surgery, radiotherapy, chemotherapy, targeted therapy and immune checkpoint inhibitors. As one of the traditional treatment methods, radiotherapy plays an important role in the treatment of all stages of NSCLC, and its immunomodulatory effect has attracted much attention. The application of immune checkpoint inhibitors (ICIs) has significantly improved the prognosis of patients with local-advanced and advanced NSCLC, but the benefit population was limited. At present, the treatment mode of radiotherapy combined with ICIs has become the focus of research. This paper reviews the research progress of radiotherapy combined with ICIs in the treatment of NSCLC.ZHU KuikuiWU GangMagazine House of Cancer Research on Prevention and Treatmentarticlenon-small cell lung cancerradiotherapyimmune checkpoint inhibitorsNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ZHZhongliu Fangzhi Yanjiu, Vol 48, Iss 10, Pp 916-921 (2021) |
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non-small cell lung cancer radiotherapy immune checkpoint inhibitors Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
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non-small cell lung cancer radiotherapy immune checkpoint inhibitors Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 ZHU Kuikui WU Gang Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC |
description |
Lung cancer is the leading cause of cancer-related deaths across the world, of which non-small cell lung cancer (NSCLC) accounts for 85%, and more than 50% of NSCLC patients were diagnosed with distant metastasis. The comprehensive treatment of NSCLC includes surgery, radiotherapy, chemotherapy, targeted therapy and immune checkpoint inhibitors. As one of the traditional treatment methods, radiotherapy plays an important role in the treatment of all stages of NSCLC, and its immunomodulatory effect has attracted much attention. The application of immune checkpoint inhibitors (ICIs) has significantly improved the prognosis of patients with local-advanced and advanced NSCLC, but the benefit population was limited. At present, the treatment mode of radiotherapy combined with ICIs has become the focus of research. This paper reviews the research progress of radiotherapy combined with ICIs in the treatment of NSCLC. |
format |
article |
author |
ZHU Kuikui WU Gang |
author_facet |
ZHU Kuikui WU Gang |
author_sort |
ZHU Kuikui |
title |
Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC |
title_short |
Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC |
title_full |
Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC |
title_fullStr |
Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC |
title_full_unstemmed |
Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC |
title_sort |
clinical research progress of radiotherapy combined with immune checkpoint inhibitors on nsclc |
publisher |
Magazine House of Cancer Research on Prevention and Treatment |
publishDate |
2021 |
url |
https://doaj.org/article/285b3c127ca447da9782f43b0837486a |
work_keys_str_mv |
AT zhukuikui clinicalresearchprogressofradiotherapycombinedwithimmunecheckpointinhibitorsonnsclc AT wugang clinicalresearchprogressofradiotherapycombinedwithimmunecheckpointinhibitorsonnsclc |
_version_ |
1718444518000295936 |