Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC

Lung cancer is the leading cause of cancer-related deaths across the world, of which non-small cell lung cancer (NSCLC) accounts for 85%, and more than 50% of NSCLC patients were diagnosed with distant metastasis. The comprehensive treatment of NSCLC includes surgery, radiotherapy, chemotherapy, tar...

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Autores principales: ZHU Kuikui, WU Gang
Formato: article
Lenguaje:ZH
Publicado: Magazine House of Cancer Research on Prevention and Treatment 2021
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Acceso en línea:https://doaj.org/article/285b3c127ca447da9782f43b0837486a
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spelling oai:doaj.org-article:285b3c127ca447da9782f43b0837486a2021-11-05T02:22:52ZClinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC1000-857810.3971/j.issn.1000-8578.2021.21.0382https://doaj.org/article/285b3c127ca447da9782f43b0837486a2021-10-01T00:00:00Zhttp://html.rhhz.net/ZLFZYJ/html/8578.2021.21.0382.htmhttps://doaj.org/toc/1000-8578Lung cancer is the leading cause of cancer-related deaths across the world, of which non-small cell lung cancer (NSCLC) accounts for 85%, and more than 50% of NSCLC patients were diagnosed with distant metastasis. The comprehensive treatment of NSCLC includes surgery, radiotherapy, chemotherapy, targeted therapy and immune checkpoint inhibitors. As one of the traditional treatment methods, radiotherapy plays an important role in the treatment of all stages of NSCLC, and its immunomodulatory effect has attracted much attention. The application of immune checkpoint inhibitors (ICIs) has significantly improved the prognosis of patients with local-advanced and advanced NSCLC, but the benefit population was limited. At present, the treatment mode of radiotherapy combined with ICIs has become the focus of research. This paper reviews the research progress of radiotherapy combined with ICIs in the treatment of NSCLC.ZHU KuikuiWU GangMagazine House of Cancer Research on Prevention and Treatmentarticlenon-small cell lung cancerradiotherapyimmune checkpoint inhibitorsNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ZHZhongliu Fangzhi Yanjiu, Vol 48, Iss 10, Pp 916-921 (2021)
institution DOAJ
collection DOAJ
language ZH
topic non-small cell lung cancer
radiotherapy
immune checkpoint inhibitors
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle non-small cell lung cancer
radiotherapy
immune checkpoint inhibitors
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
ZHU Kuikui
WU Gang
Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC
description Lung cancer is the leading cause of cancer-related deaths across the world, of which non-small cell lung cancer (NSCLC) accounts for 85%, and more than 50% of NSCLC patients were diagnosed with distant metastasis. The comprehensive treatment of NSCLC includes surgery, radiotherapy, chemotherapy, targeted therapy and immune checkpoint inhibitors. As one of the traditional treatment methods, radiotherapy plays an important role in the treatment of all stages of NSCLC, and its immunomodulatory effect has attracted much attention. The application of immune checkpoint inhibitors (ICIs) has significantly improved the prognosis of patients with local-advanced and advanced NSCLC, but the benefit population was limited. At present, the treatment mode of radiotherapy combined with ICIs has become the focus of research. This paper reviews the research progress of radiotherapy combined with ICIs in the treatment of NSCLC.
format article
author ZHU Kuikui
WU Gang
author_facet ZHU Kuikui
WU Gang
author_sort ZHU Kuikui
title Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC
title_short Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC
title_full Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC
title_fullStr Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC
title_full_unstemmed Clinical Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors on NSCLC
title_sort clinical research progress of radiotherapy combined with immune checkpoint inhibitors on nsclc
publisher Magazine House of Cancer Research on Prevention and Treatment
publishDate 2021
url https://doaj.org/article/285b3c127ca447da9782f43b0837486a
work_keys_str_mv AT zhukuikui clinicalresearchprogressofradiotherapycombinedwithimmunecheckpointinhibitorsonnsclc
AT wugang clinicalresearchprogressofradiotherapycombinedwithimmunecheckpointinhibitorsonnsclc
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