Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma

The intrinsic drivers of glioblastoma (GBM) migration are still poorly understood. Here the authors purify GBM stem cells (GSCs) from patients and profile chromatin accessibility in these cells, identifying TEAD1 as a regulator of migration in human glioblastoma.

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Detalles Bibliográficos
Autores principales: Jessica Tome-Garcia, Parsa Erfani, German Nudelman, Alexander M. Tsankov, Igor Katsyv, Rut Tejero, Bin Zhang, Martin Walsh, Roland H. Friedel, Elena Zaslavsky, Nadejda M. Tsankova
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/2866f4fd16df494d96b315c2101ad08d
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Sumario:The intrinsic drivers of glioblastoma (GBM) migration are still poorly understood. Here the authors purify GBM stem cells (GSCs) from patients and profile chromatin accessibility in these cells, identifying TEAD1 as a regulator of migration in human glioblastoma.