Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma

The intrinsic drivers of glioblastoma (GBM) migration are still poorly understood. Here the authors purify GBM stem cells (GSCs) from patients and profile chromatin accessibility in these cells, identifying TEAD1 as a regulator of migration in human glioblastoma.

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Autores principales:	Jessica Tome-Garcia, Parsa Erfani, German Nudelman, Alexander M. Tsankov, Igor Katsyv, Rut Tejero, Bin Zhang, Martin Walsh, Roland H. Friedel, Elena Zaslavsky, Nadejda M. Tsankova
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2866f4fd16df494d96b315c2101ad08d
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spelling	oai:doaj.org-article:2866f4fd16df494d96b315c2101ad08d2021-12-02T15:34:40ZAnalysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma10.1038/s41467-018-06258-22041-1723https://doaj.org/article/2866f4fd16df494d96b315c2101ad08d2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06258-2https://doaj.org/toc/2041-1723The intrinsic drivers of glioblastoma (GBM) migration are still poorly understood. Here the authors purify GBM stem cells (GSCs) from patients and profile chromatin accessibility in these cells, identifying TEAD1 as a regulator of migration in human glioblastoma.Jessica Tome-GarciaParsa ErfaniGerman NudelmanAlexander M. TsankovIgor KatsyvRut TejeroBin ZhangMartin WalshRoland H. FriedelElena ZaslavskyNadejda M. TsankovaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jessica Tome-Garcia Parsa Erfani German Nudelman Alexander M. Tsankov Igor Katsyv Rut Tejero Bin Zhang Martin Walsh Roland H. Friedel Elena Zaslavsky Nadejda M. Tsankova Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma
description	The intrinsic drivers of glioblastoma (GBM) migration are still poorly understood. Here the authors purify GBM stem cells (GSCs) from patients and profile chromatin accessibility in these cells, identifying TEAD1 as a regulator of migration in human glioblastoma.
format	article
author	Jessica Tome-Garcia Parsa Erfani German Nudelman Alexander M. Tsankov Igor Katsyv Rut Tejero Bin Zhang Martin Walsh Roland H. Friedel Elena Zaslavsky Nadejda M. Tsankova
author_facet	Jessica Tome-Garcia Parsa Erfani German Nudelman Alexander M. Tsankov Igor Katsyv Rut Tejero Bin Zhang Martin Walsh Roland H. Friedel Elena Zaslavsky Nadejda M. Tsankova
author_sort	Jessica Tome-Garcia
title	Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma
title_short	Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma
title_full	Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma
title_fullStr	Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma
title_full_unstemmed	Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma
title_sort	analysis of chromatin accessibility uncovers tead1 as a regulator of migration in human glioblastoma
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/2866f4fd16df494d96b315c2101ad08d
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Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma

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