Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer

Resveratrol is one of the most investigated polyphenols for its multiple biological activities and many beneficial effects. These are mainly related to its ability to scavenge free radicals and reduce oxidative stress. Resveratrol has also been shown to have the ability to stimulate the production o...

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Autores principales: Alessandra Quarta, Antonio Gaballo, Biswajita Pradhan, Srimanta Patra, Mrutyunjay Jena, Andrea Ragusa
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/2867d77468ef4318b84906ef0ea4f833
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spelling oai:doaj.org-article:2867d77468ef4318b84906ef0ea4f8332021-11-25T16:43:14ZBeneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer10.3390/app1122110412076-3417https://doaj.org/article/2867d77468ef4318b84906ef0ea4f8332021-11-01T00:00:00Zhttps://www.mdpi.com/2076-3417/11/22/11041https://doaj.org/toc/2076-3417Resveratrol is one of the most investigated polyphenols for its multiple biological activities and many beneficial effects. These are mainly related to its ability to scavenge free radicals and reduce oxidative stress. Resveratrol has also been shown to have the ability to stimulate the production of antioxidant enzymes, which interact with numerous signaling pathways involved in tumor development, and to possess side effects associated with the use of chemotherapy drugs. In this review article we summarized the main discoveries about the impact resveratrol can have in helping to prevent, as well as adjuvant treating, breast cancer. A brief overview of the primary sources of resveratrol as well as some approaches for improving its bioavailability have been also discussed.Alessandra QuartaAntonio GaballoBiswajita PradhanSrimanta PatraMrutyunjay JenaAndrea RagusaMDPI AGarticleresveratrolreactive oxygen speciesbreast cancerantioxidantspolyphenolsoxidative stressTechnologyTEngineering (General). Civil engineering (General)TA1-2040Biology (General)QH301-705.5PhysicsQC1-999ChemistryQD1-999ENApplied Sciences, Vol 11, Iss 11041, p 11041 (2021)
institution DOAJ
collection DOAJ
language EN
topic resveratrol
reactive oxygen species
breast cancer
antioxidants
polyphenols
oxidative stress
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
spellingShingle resveratrol
reactive oxygen species
breast cancer
antioxidants
polyphenols
oxidative stress
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
Alessandra Quarta
Antonio Gaballo
Biswajita Pradhan
Srimanta Patra
Mrutyunjay Jena
Andrea Ragusa
Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer
description Resveratrol is one of the most investigated polyphenols for its multiple biological activities and many beneficial effects. These are mainly related to its ability to scavenge free radicals and reduce oxidative stress. Resveratrol has also been shown to have the ability to stimulate the production of antioxidant enzymes, which interact with numerous signaling pathways involved in tumor development, and to possess side effects associated with the use of chemotherapy drugs. In this review article we summarized the main discoveries about the impact resveratrol can have in helping to prevent, as well as adjuvant treating, breast cancer. A brief overview of the primary sources of resveratrol as well as some approaches for improving its bioavailability have been also discussed.
format article
author Alessandra Quarta
Antonio Gaballo
Biswajita Pradhan
Srimanta Patra
Mrutyunjay Jena
Andrea Ragusa
author_facet Alessandra Quarta
Antonio Gaballo
Biswajita Pradhan
Srimanta Patra
Mrutyunjay Jena
Andrea Ragusa
author_sort Alessandra Quarta
title Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer
title_short Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer
title_full Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer
title_fullStr Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer
title_full_unstemmed Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer
title_sort beneficial oxidative stress-related <i>trans</i>-resveratrol effects in the treatment and prevention of breast cancer
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/2867d77468ef4318b84906ef0ea4f833
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