Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer
Resveratrol is one of the most investigated polyphenols for its multiple biological activities and many beneficial effects. These are mainly related to its ability to scavenge free radicals and reduce oxidative stress. Resveratrol has also been shown to have the ability to stimulate the production o...
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2021
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oai:doaj.org-article:2867d77468ef4318b84906ef0ea4f8332021-11-25T16:43:14ZBeneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer10.3390/app1122110412076-3417https://doaj.org/article/2867d77468ef4318b84906ef0ea4f8332021-11-01T00:00:00Zhttps://www.mdpi.com/2076-3417/11/22/11041https://doaj.org/toc/2076-3417Resveratrol is one of the most investigated polyphenols for its multiple biological activities and many beneficial effects. These are mainly related to its ability to scavenge free radicals and reduce oxidative stress. Resveratrol has also been shown to have the ability to stimulate the production of antioxidant enzymes, which interact with numerous signaling pathways involved in tumor development, and to possess side effects associated with the use of chemotherapy drugs. In this review article we summarized the main discoveries about the impact resveratrol can have in helping to prevent, as well as adjuvant treating, breast cancer. A brief overview of the primary sources of resveratrol as well as some approaches for improving its bioavailability have been also discussed.Alessandra QuartaAntonio GaballoBiswajita PradhanSrimanta PatraMrutyunjay JenaAndrea RagusaMDPI AGarticleresveratrolreactive oxygen speciesbreast cancerantioxidantspolyphenolsoxidative stressTechnologyTEngineering (General). Civil engineering (General)TA1-2040Biology (General)QH301-705.5PhysicsQC1-999ChemistryQD1-999ENApplied Sciences, Vol 11, Iss 11041, p 11041 (2021) |
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resveratrol reactive oxygen species breast cancer antioxidants polyphenols oxidative stress Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999 |
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resveratrol reactive oxygen species breast cancer antioxidants polyphenols oxidative stress Technology T Engineering (General). Civil engineering (General) TA1-2040 Biology (General) QH301-705.5 Physics QC1-999 Chemistry QD1-999 Alessandra Quarta Antonio Gaballo Biswajita Pradhan Srimanta Patra Mrutyunjay Jena Andrea Ragusa Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer |
description |
Resveratrol is one of the most investigated polyphenols for its multiple biological activities and many beneficial effects. These are mainly related to its ability to scavenge free radicals and reduce oxidative stress. Resveratrol has also been shown to have the ability to stimulate the production of antioxidant enzymes, which interact with numerous signaling pathways involved in tumor development, and to possess side effects associated with the use of chemotherapy drugs. In this review article we summarized the main discoveries about the impact resveratrol can have in helping to prevent, as well as adjuvant treating, breast cancer. A brief overview of the primary sources of resveratrol as well as some approaches for improving its bioavailability have been also discussed. |
format |
article |
author |
Alessandra Quarta Antonio Gaballo Biswajita Pradhan Srimanta Patra Mrutyunjay Jena Andrea Ragusa |
author_facet |
Alessandra Quarta Antonio Gaballo Biswajita Pradhan Srimanta Patra Mrutyunjay Jena Andrea Ragusa |
author_sort |
Alessandra Quarta |
title |
Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer |
title_short |
Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer |
title_full |
Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer |
title_fullStr |
Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer |
title_full_unstemmed |
Beneficial Oxidative Stress-Related <i>trans</i>-Resveratrol Effects in the Treatment and Prevention of Breast Cancer |
title_sort |
beneficial oxidative stress-related <i>trans</i>-resveratrol effects in the treatment and prevention of breast cancer |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/2867d77468ef4318b84906ef0ea4f833 |
work_keys_str_mv |
AT alessandraquarta beneficialoxidativestressrelateditransiresveratroleffectsinthetreatmentandpreventionofbreastcancer AT antoniogaballo beneficialoxidativestressrelateditransiresveratroleffectsinthetreatmentandpreventionofbreastcancer AT biswajitapradhan beneficialoxidativestressrelateditransiresveratroleffectsinthetreatmentandpreventionofbreastcancer AT srimantapatra beneficialoxidativestressrelateditransiresveratroleffectsinthetreatmentandpreventionofbreastcancer AT mrutyunjayjena beneficialoxidativestressrelateditransiresveratroleffectsinthetreatmentandpreventionofbreastcancer AT andrearagusa beneficialoxidativestressrelateditransiresveratroleffectsinthetreatmentandpreventionofbreastcancer |
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