ASSESSMENT OF THE STEROID THERAPY EFFECTIVENESS IN COMPLEX TREATMENT OF ACUTE PURULENT RHINOSINUSITIS IN CHILDREN

Material and methods. The control group consisted of 166 children with acute purulent rhinosinusitis who underwent standard treatment: antibiotic therapy, on the strict condition - endonasal drainage of the maxillary sinuses, the treatment method around Proets, physiotherapy of the nose, vasoconstri...

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Autor principal:	O. V. Borovikova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	acute purulent rhinosinusitis in children inhalative topical glucocorticosteroid Science Q
Acceso en línea:	https://doaj.org/article/287d258e911e46f1b45d697512b3fd22
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spelling	oai:doaj.org-article:287d258e911e46f1b45d697512b3fd222021-11-23T06:14:37ZASSESSMENT OF THE STEROID THERAPY EFFECTIVENESS IN COMPLEX TREATMENT OF ACUTE PURULENT RHINOSINUSITIS IN CHILDREN2541-94202587-959610.12737/article_5955e6b458cc60.57462709https://doaj.org/article/287d258e911e46f1b45d697512b3fd222017-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/356https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Material and methods. The control group consisted of 166 children with acute purulent rhinosinusitis who underwent standard treatment: antibiotic therapy, on the strict condition - endonasal drainage of the maxillary sinuses, the treatment method around Proets, physiotherapy of the nose, vasoconstrictor nose drops. The main group consisted of 132 children with acute purulent rhinosinusitis, who, in addition to standard treatment, were prescribed topical corticosteroid - mometasone furoate. Results. The concentration of lactoferrin (in the main group) was normalized due to the action of the nasonex spray, which proves a high anti-inflammatory effect of the combined treatment. There was a statistically significant difference in the groups after 7 days and 1 month after treatment (t = 1.96; p = 0.05). Based on the data of Mac-Nimar criterion (X2 = 11.204, with the probability of error p = 0.002) in the control group compared to the primary (x2=9.202, with the probability of error p < 0.0001), treatment was less effective. Conclusion. The use of inhalative topical glucocorticosteroid in treatment of children with acute purulent rhinosinusitis allows to achieve a positive clinical effect and the concentration of lactoferrin can serve as an important criterion of the effectiveness of treatment.O. V. BorovikovaScientific Сentre for Family Health and Human Reproduction Problemsarticleacute purulent rhinosinusitis in childreninhalative topical glucocorticosteroidScienceQRUActa Biomedica Scientifica, Vol 2, Iss 1, Pp 24-27 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	acute purulent rhinosinusitis in children inhalative topical glucocorticosteroid Science Q
spellingShingle	acute purulent rhinosinusitis in children inhalative topical glucocorticosteroid Science Q O. V. Borovikova ASSESSMENT OF THE STEROID THERAPY EFFECTIVENESS IN COMPLEX TREATMENT OF ACUTE PURULENT RHINOSINUSITIS IN CHILDREN
description	Material and methods. The control group consisted of 166 children with acute purulent rhinosinusitis who underwent standard treatment: antibiotic therapy, on the strict condition - endonasal drainage of the maxillary sinuses, the treatment method around Proets, physiotherapy of the nose, vasoconstrictor nose drops. The main group consisted of 132 children with acute purulent rhinosinusitis, who, in addition to standard treatment, were prescribed topical corticosteroid - mometasone furoate. Results. The concentration of lactoferrin (in the main group) was normalized due to the action of the nasonex spray, which proves a high anti-inflammatory effect of the combined treatment. There was a statistically significant difference in the groups after 7 days and 1 month after treatment (t = 1.96; p = 0.05). Based on the data of Mac-Nimar criterion (X2 = 11.204, with the probability of error p = 0.002) in the control group compared to the primary (x2=9.202, with the probability of error p < 0.0001), treatment was less effective. Conclusion. The use of inhalative topical glucocorticosteroid in treatment of children with acute purulent rhinosinusitis allows to achieve a positive clinical effect and the concentration of lactoferrin can serve as an important criterion of the effectiveness of treatment.
format	article
author	O. V. Borovikova
author_facet	O. V. Borovikova
author_sort	O. V. Borovikova
title	ASSESSMENT OF THE STEROID THERAPY EFFECTIVENESS IN COMPLEX TREATMENT OF ACUTE PURULENT RHINOSINUSITIS IN CHILDREN
title_short	ASSESSMENT OF THE STEROID THERAPY EFFECTIVENESS IN COMPLEX TREATMENT OF ACUTE PURULENT RHINOSINUSITIS IN CHILDREN
title_full	ASSESSMENT OF THE STEROID THERAPY EFFECTIVENESS IN COMPLEX TREATMENT OF ACUTE PURULENT RHINOSINUSITIS IN CHILDREN
title_fullStr	ASSESSMENT OF THE STEROID THERAPY EFFECTIVENESS IN COMPLEX TREATMENT OF ACUTE PURULENT RHINOSINUSITIS IN CHILDREN
title_full_unstemmed	ASSESSMENT OF THE STEROID THERAPY EFFECTIVENESS IN COMPLEX TREATMENT OF ACUTE PURULENT RHINOSINUSITIS IN CHILDREN
title_sort	assessment of the steroid therapy effectiveness in complex treatment of acute purulent rhinosinusitis in children
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/287d258e911e46f1b45d697512b3fd22
work_keys_str_mv	AT ovborovikova assessmentofthesteroidtherapyeffectivenessincomplextreatmentofacutepurulentrhinosinusitisinchildren
_version_	1718416995905437696

ASSESSMENT OF THE STEROID THERAPY EFFECTIVENESS IN COMPLEX TREATMENT OF ACUTE PURULENT RHINOSINUSITIS IN CHILDREN

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