High-intensity focused ultrasound ablation as an adjuvant surgical salvage procedure in gestational trophoblastic neoplasia chemotherapy with chemoresistance or recurrence: two case reports

Background Chemotherapy is the main treatment strategy for gestational trophoblastic neoplasia (GTN). Surgical resection is crucial to deal with chemoresistance and recurrence following chemotherapy. The aim of this study was to explore if high-intensity focused ultrasound (HIFU) can be used as a co...

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Autores principales:	Chaokun She, Sha Li, Xiaojun Wang, Xianghui Lu, Hao Liang, Xiaoyun Liu
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2021
Materias:	chemoresistance chemotherapy gestational trophoblastic neoplasia high intensity focused ultrasound (hifu) recurrence Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/287f3c2d77d94b759de277c86d38e2f7
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spelling	oai:doaj.org-article:287f3c2d77d94b759de277c86d38e2f72021-11-04T15:00:41ZHigh-intensity focused ultrasound ablation as an adjuvant surgical salvage procedure in gestational trophoblastic neoplasia chemotherapy with chemoresistance or recurrence: two case reports0265-67361464-515710.1080/02656736.2021.1998659https://doaj.org/article/287f3c2d77d94b759de277c86d38e2f72021-01-01T00:00:00Zhttp://dx.doi.org/10.1080/02656736.2021.1998659https://doaj.org/toc/0265-6736https://doaj.org/toc/1464-5157Background Chemotherapy is the main treatment strategy for gestational trophoblastic neoplasia (GTN). Surgical resection is crucial to deal with chemoresistance and recurrence following chemotherapy. The aim of this study was to explore if high-intensity focused ultrasound (HIFU) can be used as a complementary technique to surgical procedures in the management of GTN. Case report This case report described two females who previously developed chemoresistance or recurrence during chemotherapy and then underwent HIFU as an adjuvant surgical salvage procedure. For high-risk GTN patients with chemoresistance, HIFU treatment decreased the risk of chemoresistance and shortened the course of chemotherapy. It also reduced the dosage of chemotherapeutic agents used for the patient who suffered a recurrence. Conclusion For patients with GTN who desire to preserve their uterus, HIFU may be used as a complementary technique to surgical resection in the management of GTN.Chaokun SheSha LiXiaojun WangXianghui LuHao LiangXiaoyun LiuTaylor & Francis Grouparticlechemoresistancechemotherapygestational trophoblastic neoplasiahigh intensity focused ultrasound (hifu)recurrenceMedical technologyR855-855.5ENInternational Journal of Hyperthermia, Vol 38, Iss 1, Pp 1584-1589 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	chemoresistance chemotherapy gestational trophoblastic neoplasia high intensity focused ultrasound (hifu) recurrence Medical technology R855-855.5
spellingShingle	chemoresistance chemotherapy gestational trophoblastic neoplasia high intensity focused ultrasound (hifu) recurrence Medical technology R855-855.5 Chaokun She Sha Li Xiaojun Wang Xianghui Lu Hao Liang Xiaoyun Liu High-intensity focused ultrasound ablation as an adjuvant surgical salvage procedure in gestational trophoblastic neoplasia chemotherapy with chemoresistance or recurrence: two case reports
description	Background Chemotherapy is the main treatment strategy for gestational trophoblastic neoplasia (GTN). Surgical resection is crucial to deal with chemoresistance and recurrence following chemotherapy. The aim of this study was to explore if high-intensity focused ultrasound (HIFU) can be used as a complementary technique to surgical procedures in the management of GTN. Case report This case report described two females who previously developed chemoresistance or recurrence during chemotherapy and then underwent HIFU as an adjuvant surgical salvage procedure. For high-risk GTN patients with chemoresistance, HIFU treatment decreased the risk of chemoresistance and shortened the course of chemotherapy. It also reduced the dosage of chemotherapeutic agents used for the patient who suffered a recurrence. Conclusion For patients with GTN who desire to preserve their uterus, HIFU may be used as a complementary technique to surgical resection in the management of GTN.
format	article
author	Chaokun She Sha Li Xiaojun Wang Xianghui Lu Hao Liang Xiaoyun Liu
author_facet	Chaokun She Sha Li Xiaojun Wang Xianghui Lu Hao Liang Xiaoyun Liu
author_sort	Chaokun She
title	High-intensity focused ultrasound ablation as an adjuvant surgical salvage procedure in gestational trophoblastic neoplasia chemotherapy with chemoresistance or recurrence: two case reports
title_short	High-intensity focused ultrasound ablation as an adjuvant surgical salvage procedure in gestational trophoblastic neoplasia chemotherapy with chemoresistance or recurrence: two case reports
title_full	High-intensity focused ultrasound ablation as an adjuvant surgical salvage procedure in gestational trophoblastic neoplasia chemotherapy with chemoresistance or recurrence: two case reports
title_fullStr	High-intensity focused ultrasound ablation as an adjuvant surgical salvage procedure in gestational trophoblastic neoplasia chemotherapy with chemoresistance or recurrence: two case reports
title_full_unstemmed	High-intensity focused ultrasound ablation as an adjuvant surgical salvage procedure in gestational trophoblastic neoplasia chemotherapy with chemoresistance or recurrence: two case reports
title_sort	high-intensity focused ultrasound ablation as an adjuvant surgical salvage procedure in gestational trophoblastic neoplasia chemotherapy with chemoresistance or recurrence: two case reports
publisher	Taylor & Francis Group
publishDate	2021
url	https://doaj.org/article/287f3c2d77d94b759de277c86d38e2f7
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High-intensity focused ultrasound ablation as an adjuvant surgical salvage procedure in gestational trophoblastic neoplasia chemotherapy with chemoresistance or recurrence: two case reports

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