Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection
Here, following a patient with severe acute Pseudomonas aeruginosa infection, the authors combine comprehensive isolate characterization from lung and gut samples (>100 isolates) and patient clinical data to provide insights into bacterial responses to antibiotic therapy.
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Nature Portfolio
2021
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oai:doaj.org-article:288e3c2784b04e7b8be0262d7398b88b2021-12-02T13:41:42ZRapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection10.1038/s41467-021-22814-92041-1723https://doaj.org/article/288e3c2784b04e7b8be0262d7398b88b2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22814-9https://doaj.org/toc/2041-1723Here, following a patient with severe acute Pseudomonas aeruginosa infection, the authors combine comprehensive isolate characterization from lung and gut samples (>100 isolates) and patient clinical data to provide insights into bacterial responses to antibiotic therapy.Rachel WheatleyJulio Diaz CaballeroNatalia KapelFien H. R. de WinterPramod JangirAngus QuinnEster del Barrio-TofiñoCarla López-CausapéJessica HedgeGabriel TorrensThomas Van der SchalkBasil Britto XavierFelipe Fernández-CuencaAngel ArenzanaClaudia RecanatiniLeen TimbermontFrangiscos SifakisAlexey RuzinOmar AliChristine LammensHerman GoossensJan KluytmansSamir Kumar-SinghAntonio OliverSurbhi Malhotra-KumarCraig MacLeanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
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DOAJ |
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DOAJ |
| language |
EN |
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Science Q |
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Science Q Rachel Wheatley Julio Diaz Caballero Natalia Kapel Fien H. R. de Winter Pramod Jangir Angus Quinn Ester del Barrio-Tofiño Carla López-Causapé Jessica Hedge Gabriel Torrens Thomas Van der Schalk Basil Britto Xavier Felipe Fernández-Cuenca Angel Arenzana Claudia Recanatini Leen Timbermont Frangiscos Sifakis Alexey Ruzin Omar Ali Christine Lammens Herman Goossens Jan Kluytmans Samir Kumar-Singh Antonio Oliver Surbhi Malhotra-Kumar Craig MacLean Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection |
| description |
Here, following a patient with severe acute Pseudomonas aeruginosa infection, the authors combine comprehensive isolate characterization from lung and gut samples (>100 isolates) and patient clinical data to provide insights into bacterial responses to antibiotic therapy. |
| format |
article |
| author |
Rachel Wheatley Julio Diaz Caballero Natalia Kapel Fien H. R. de Winter Pramod Jangir Angus Quinn Ester del Barrio-Tofiño Carla López-Causapé Jessica Hedge Gabriel Torrens Thomas Van der Schalk Basil Britto Xavier Felipe Fernández-Cuenca Angel Arenzana Claudia Recanatini Leen Timbermont Frangiscos Sifakis Alexey Ruzin Omar Ali Christine Lammens Herman Goossens Jan Kluytmans Samir Kumar-Singh Antonio Oliver Surbhi Malhotra-Kumar Craig MacLean |
| author_facet |
Rachel Wheatley Julio Diaz Caballero Natalia Kapel Fien H. R. de Winter Pramod Jangir Angus Quinn Ester del Barrio-Tofiño Carla López-Causapé Jessica Hedge Gabriel Torrens Thomas Van der Schalk Basil Britto Xavier Felipe Fernández-Cuenca Angel Arenzana Claudia Recanatini Leen Timbermont Frangiscos Sifakis Alexey Ruzin Omar Ali Christine Lammens Herman Goossens Jan Kluytmans Samir Kumar-Singh Antonio Oliver Surbhi Malhotra-Kumar Craig MacLean |
| author_sort |
Rachel Wheatley |
| title |
Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection |
| title_short |
Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection |
| title_full |
Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection |
| title_fullStr |
Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection |
| title_full_unstemmed |
Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection |
| title_sort |
rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute pseudomonas aeruginosa infection |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/288e3c2784b04e7b8be0262d7398b88b |
| work_keys_str_mv |
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