Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection

Here, following a patient with severe acute Pseudomonas aeruginosa infection, the authors combine comprehensive isolate characterization from lung and gut samples (>100 isolates) and patient clinical data to provide insights into bacterial responses to antibiotic therapy.

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Bibliographic Details
Main Authors: Rachel Wheatley, Julio Diaz Caballero, Natalia Kapel, Fien H. R. de Winter, Pramod Jangir, Angus Quinn, Ester del Barrio-Tofiño, Carla López-Causapé, Jessica Hedge, Gabriel Torrens, Thomas Van der Schalk, Basil Britto Xavier, Felipe Fernández-Cuenca, Angel Arenzana, Claudia Recanatini, Leen Timbermont, Frangiscos Sifakis, Alexey Ruzin, Omar Ali, Christine Lammens, Herman Goossens, Jan Kluytmans, Samir Kumar-Singh, Antonio Oliver, Surbhi Malhotra-Kumar, Craig MacLean
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/288e3c2784b04e7b8be0262d7398b88b
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