Discovery of novel antituberculosis agents among 3-phenyl-5-(1-phenyl-1H-[1,2,3]triazol-4-yl)-[1,2,4]oxadiazole derivatives targeting aminoacyl-tRNA synthetases

Abstract Antibiotic resistance is a major problem of tuberculosis treatment. This provides the stimulus for the search of novel molecular targets and approaches to reduce or forestall resistance emergence in Mycobacterium tuberculosis. Earlier, we discovered a novel small-molecular inhibitor among 3...

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Autores principales: Mariia Yu. Rybak, Anatoliy O. Balanda, Anna P. Yatsyshyna, Igor. M. Kotey, Sergiy A. Starosyla, Volodymyr G. Bdzhola, Lubov L. Lukash, Sergiy M. Yarmoluk, Michael A. Tukalo, Galyna P. Volynets
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2895faeaf24341efba42a3825c6db018
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