Impact of weight variability on mortality among Korean men and women: a population based study

Abstract The health consequences of weight fluctuation have been controversial and little-studied within Asian populations. We aimed to determine the effect of weight variability on mortality using Korean National Health Insurance Service – National Health Screening Cohort. Weight variability was de...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Daein Choi, Seulggie Choi, Sang Min Park
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2897ee41384e43a4973b4257949c01a0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2897ee41384e43a4973b4257949c01a0
record_format	dspace
spelling	oai:doaj.org-article:2897ee41384e43a4973b4257949c01a02021-12-02T15:09:40ZImpact of weight variability on mortality among Korean men and women: a population based study10.1038/s41598-019-46037-72045-2322https://doaj.org/article/2897ee41384e43a4973b4257949c01a02019-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-019-46037-7https://doaj.org/toc/2045-2322Abstract The health consequences of weight fluctuation have been controversial and little-studied within Asian populations. We aimed to determine the effect of weight variability on mortality using Korean National Health Insurance Service – National Health Screening Cohort. Weight variability was defined as the average successive variability of body mass index (BMI) of the first (2002 and 2003), second (2004 and 2005), and third (2006 and 2007) health examinations. Then, we used Cox regression models to estimate the effect of weight variability on mortality. Compared to participants within the first quintile (lowest) of weight variability, those within the fifth quintile (highest) had increased the risk of death from all causes (hazard ratio, HR 1.33, 95% confidence interval, CI 1.26–1.41), cardiovascular disease (HR 1.31, 95% CI 1.12–1.53), cancer (HR 1.11, 95% CI 1.02–1.22), and other causes (HR 1.58, 95% CI 1.45–1.73). The risk-increasing effect of weight variability on mortality was preserved after excluding past and current smokers as well as those with pre-existing cardiovascular disease or cancer. In conclusion, high weight variability may lead to elevated risk of death even among healthy never smokers. Therefore, maintaining a steady weight should be recommended to benefit from reduced risk of death.Daein ChoiSeulggie ChoiSang Min ParkNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Daein Choi Seulggie Choi Sang Min Park Impact of weight variability on mortality among Korean men and women: a population based study
description	Abstract The health consequences of weight fluctuation have been controversial and little-studied within Asian populations. We aimed to determine the effect of weight variability on mortality using Korean National Health Insurance Service – National Health Screening Cohort. Weight variability was defined as the average successive variability of body mass index (BMI) of the first (2002 and 2003), second (2004 and 2005), and third (2006 and 2007) health examinations. Then, we used Cox regression models to estimate the effect of weight variability on mortality. Compared to participants within the first quintile (lowest) of weight variability, those within the fifth quintile (highest) had increased the risk of death from all causes (hazard ratio, HR 1.33, 95% confidence interval, CI 1.26–1.41), cardiovascular disease (HR 1.31, 95% CI 1.12–1.53), cancer (HR 1.11, 95% CI 1.02–1.22), and other causes (HR 1.58, 95% CI 1.45–1.73). The risk-increasing effect of weight variability on mortality was preserved after excluding past and current smokers as well as those with pre-existing cardiovascular disease or cancer. In conclusion, high weight variability may lead to elevated risk of death even among healthy never smokers. Therefore, maintaining a steady weight should be recommended to benefit from reduced risk of death.
format	article
author	Daein Choi Seulggie Choi Sang Min Park
author_facet	Daein Choi Seulggie Choi Sang Min Park
author_sort	Daein Choi
title	Impact of weight variability on mortality among Korean men and women: a population based study
title_short	Impact of weight variability on mortality among Korean men and women: a population based study
title_full	Impact of weight variability on mortality among Korean men and women: a population based study
title_fullStr	Impact of weight variability on mortality among Korean men and women: a population based study
title_full_unstemmed	Impact of weight variability on mortality among Korean men and women: a population based study
title_sort	impact of weight variability on mortality among korean men and women: a population based study
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/2897ee41384e43a4973b4257949c01a0
work_keys_str_mv	AT daeinchoi impactofweightvariabilityonmortalityamongkoreanmenandwomenapopulationbasedstudy AT seulggiechoi impactofweightvariabilityonmortalityamongkoreanmenandwomenapopulationbasedstudy AT sangminpark impactofweightvariabilityonmortalityamongkoreanmenandwomenapopulationbasedstudy
_version_	1718387801824690176

Impact of weight variability on mortality among Korean men and women: a population based study

Ejemplares similares