Characterization of the human TARDBP gene promoter

Abstract The expression of TDP-43, the main component of neuronal intracellular inclusions across a broad spectrum of ALS and FTD disorders, is developmentally regulated and studies in vivo have shown that TDP-43 overexpression can be toxic, even before observation of pathological aggregates. Starti...

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Autores principales: Marco Baralle, Maurizio Romano
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/289db9c6597a4a4c99f0b853a8df1272
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