Disordered RNA chaperones can enhance nucleic acid folding via local charge screening
RNA chaperones, such as the hepatitic C virus (HCV) core protein, are proteins that aid in the folding of nucleic acids. Here authors use single‐molecule spectroscopy and simulation to show that the HCV core protein acts as a flexible macromolecular counterion which facilitates nucleic acid folding....
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Autores principales: | Erik D. Holmstrom, Zhaowei Liu, Daniel Nettels, Robert B. Best, Benjamin Schuler |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/289f20cc4cd4465ab566f9409c9f7499 |
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