Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations

J Uy, L Fogelfeld, Y GuerraDivision of Endocrinology, Diabetes and Metabolism, John H Stroger Jr Hospital of Cook County, Chicago; Department of Endocrinology, Diabetes and Metabolism, Rush University Hospital, Chicago, IL, USAAbstract: We have now at our disposal the new rapid-acting insulin analog...

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Autores principales:	Uy J, Fogelfeld L, Guerra Y
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/28a2a29c6aa54edda42f5cf654835b30
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spelling	oai:doaj.org-article:28a2a29c6aa54edda42f5cf654835b302021-12-02T00:02:10ZCumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations1178-7007https://doaj.org/article/28a2a29c6aa54edda42f5cf654835b302012-01-01T00:00:00Zhttp://www.dovepress.com/cumulative-clinical-experience-with-use-of-insulin-lispro-critical-app-a9025https://doaj.org/toc/1178-7007J Uy, L Fogelfeld, Y GuerraDivision of Endocrinology, Diabetes and Metabolism, John H Stroger Jr Hospital of Cook County, Chicago; Department of Endocrinology, Diabetes and Metabolism, Rush University Hospital, Chicago, IL, USAAbstract: We have now at our disposal the new rapid-acting insulin analogs, of which insulin lispro was the first to become commercially available. While the differences in pharmacokinetic and pharmacodynamic characteristics are indisputable, the clinical benefits attained by these changes have not been as clear. In the present review, we discuss the structure, pharmacology, and landmark studies related to insulin lispro. The clinical characteristics of insulin lispro are compared with those of insulin regular and other insulin analogs in different clinical situations. Also included are the aspects of quality of life and cost-effectiveness that may modify the modern practitioner&#39;s decision to adopt one type of insulin over another.Keywords: insulin lispro, rapid-acting, insulin, analogUy JFogelfeld LGuerra YDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2012, Iss default, Pp 1-10 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Uy J Fogelfeld L Guerra Y Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations
description	J Uy, L Fogelfeld, Y GuerraDivision of Endocrinology, Diabetes and Metabolism, John H Stroger Jr Hospital of Cook County, Chicago; Department of Endocrinology, Diabetes and Metabolism, Rush University Hospital, Chicago, IL, USAAbstract: We have now at our disposal the new rapid-acting insulin analogs, of which insulin lispro was the first to become commercially available. While the differences in pharmacokinetic and pharmacodynamic characteristics are indisputable, the clinical benefits attained by these changes have not been as clear. In the present review, we discuss the structure, pharmacology, and landmark studies related to insulin lispro. The clinical characteristics of insulin lispro are compared with those of insulin regular and other insulin analogs in different clinical situations. Also included are the aspects of quality of life and cost-effectiveness that may modify the modern practitioner&#39;s decision to adopt one type of insulin over another.Keywords: insulin lispro, rapid-acting, insulin, analog
format	article
author	Uy J Fogelfeld L Guerra Y
author_facet	Uy J Fogelfeld L Guerra Y
author_sort	Uy J
title	Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations
title_short	Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations
title_full	Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations
title_fullStr	Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations
title_full_unstemmed	Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations
title_sort	cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/28a2a29c6aa54edda42f5cf654835b30
work_keys_str_mv	AT uyj cumulativeclinicalexperiencewithuseofinsulinlisprocriticalappraisalroleintherapyandpatientconsiderations AT fogelfeldl cumulativeclinicalexperiencewithuseofinsulinlisprocriticalappraisalroleintherapyandpatientconsiderations AT guerray cumulativeclinicalexperiencewithuseofinsulinlisprocriticalappraisalroleintherapyandpatientconsiderations
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Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations

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