A Noncanonical Autophagy Pathway Restricts <named-content content-type="genus-species">Toxoplasma gondii</named-content> Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells

A Noncanonical Autophagy Pathway Restricts <named-content content-type="genus-species">Toxoplasma gondii</named-content> Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells

ABSTRACT A core set of autophagy proteins is required for gamma interferon (IFN-γ)-mediated clearance of Toxoplasma gondii in the mouse because of their control of several downstream effectors, including immunity-related GTPases (IRGs) and guanylate-binding proteins (GBPs). However, these effectors...

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Autores principales: Elizabeth M. Selleck, Robert C. Orchard, Kara G. Lassen, Wandy L. Beatty, Ramnik J. Xavier, Beth Levine, Herbert W. Virgin, L. David Sibley
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/28b393fbe97e4760a7ecc6c932e146bd
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