Expression of CD226 is associated to but not required for NK cell education

CD226 is an activating receptor expressed in a co-varied manner with inhibitory receptors on natural killer (NK) cells, but whether CD226 is involved in NK cell education is unclear. Here the authors show that CD226 expression is plastic depending on the MHC environment and endows educated NK cells...

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Autores principales:	Arnika K. Wagner, Nadir Kadri, Johanna Snäll, Petter Brodin, Susan Gilfillan, Marco Colonna, Günter Bernhardt, Petter Höglund, Klas Kärre, Benedict J. Chambers
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/28b3bcb3f4cd4689b0dc0566b3660a7d
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spelling	oai:doaj.org-article:28b3bcb3f4cd4689b0dc0566b3660a7d2021-12-02T15:38:53ZExpression of CD226 is associated to but not required for NK cell education10.1038/ncomms156272041-1723https://doaj.org/article/28b3bcb3f4cd4689b0dc0566b3660a7d2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15627https://doaj.org/toc/2041-1723CD226 is an activating receptor expressed in a co-varied manner with inhibitory receptors on natural killer (NK) cells, but whether CD226 is involved in NK cell education is unclear. Here the authors show that CD226 expression is plastic depending on the MHC environment and endows educated NK cells enhanced effector functions.Arnika K. WagnerNadir KadriJohanna SnällPetter BrodinSusan GilfillanMarco ColonnaGünter BernhardtPetter HöglundKlas KärreBenedict J. ChambersNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Arnika K. Wagner Nadir Kadri Johanna Snäll Petter Brodin Susan Gilfillan Marco Colonna Günter Bernhardt Petter Höglund Klas Kärre Benedict J. Chambers Expression of CD226 is associated to but not required for NK cell education
description	CD226 is an activating receptor expressed in a co-varied manner with inhibitory receptors on natural killer (NK) cells, but whether CD226 is involved in NK cell education is unclear. Here the authors show that CD226 expression is plastic depending on the MHC environment and endows educated NK cells enhanced effector functions.
format	article
author	Arnika K. Wagner Nadir Kadri Johanna Snäll Petter Brodin Susan Gilfillan Marco Colonna Günter Bernhardt Petter Höglund Klas Kärre Benedict J. Chambers
author_facet	Arnika K. Wagner Nadir Kadri Johanna Snäll Petter Brodin Susan Gilfillan Marco Colonna Günter Bernhardt Petter Höglund Klas Kärre Benedict J. Chambers
author_sort	Arnika K. Wagner
title	Expression of CD226 is associated to but not required for NK cell education
title_short	Expression of CD226 is associated to but not required for NK cell education
title_full	Expression of CD226 is associated to but not required for NK cell education
title_fullStr	Expression of CD226 is associated to but not required for NK cell education
title_full_unstemmed	Expression of CD226 is associated to but not required for NK cell education
title_sort	expression of cd226 is associated to but not required for nk cell education
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/28b3bcb3f4cd4689b0dc0566b3660a7d
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Expression of CD226 is associated to but not required for NK cell education

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