Development of Spike Receptor-Binding Domain Nanoparticles as a Vaccine Candidate against SARS-CoV-2 Infection in Ferrets

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a causative agent of the CoV disease 2019 (COVID-19) pandemic, enters host cells via the interaction of its receptor-binding domain (RBD) of the spike protein with host angiotensin-converting enzyme 2 (ACE2). Therefore, the RBD is a prom...

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Autores principales:	Young-Il Kim, Dokyun Kim, Kwang-Min Yu, Hogyu David Seo, Shin-Ae Lee, Mark Anthony B. Casel, Seung-Gyu Jang, Stephanie Kim, WooRam Jung, Chih-Jen Lai, Young Ki Choi, Jae U. Jung
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/28c7b10f0f2446b1a7fdbe067aabdadd
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spelling	oai:doaj.org-article:28c7b10f0f2446b1a7fdbe067aabdadd2021-11-03T18:56:09ZDevelopment of Spike Receptor-Binding Domain Nanoparticles as a Vaccine Candidate against SARS-CoV-2 Infection in Ferrets2150-751110.1128/mBio.00230-21https://doaj.org/article/28c7b10f0f2446b1a7fdbe067aabdadd2021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00230-21https://doaj.org/toc/2150-7511 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a causative agent of the CoV disease 2019 (COVID-19) pandemic, enters host cells via the interaction of its receptor-binding domain (RBD) of the spike protein with host angiotensin-converting enzyme 2 (ACE2). Therefore, the RBD is a promising vaccine target to induce protective immunity against SARS-CoV-2 infection.Young-Il KimDokyun KimKwang-Min YuHogyu David SeoShin-Ae LeeMark Anthony B. CaselSeung-Gyu JangStephanie KimWooRam JungChih-Jen LaiYoung Ki ChoiJae U. JungAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Young-Il Kim Dokyun Kim Kwang-Min Yu Hogyu David Seo Shin-Ae Lee Mark Anthony B. Casel Seung-Gyu Jang Stephanie Kim WooRam Jung Chih-Jen Lai Young Ki Choi Jae U. Jung Development of Spike Receptor-Binding Domain Nanoparticles as a Vaccine Candidate against SARS-CoV-2 Infection in Ferrets
description	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a causative agent of the CoV disease 2019 (COVID-19) pandemic, enters host cells via the interaction of its receptor-binding domain (RBD) of the spike protein with host angiotensin-converting enzyme 2 (ACE2). Therefore, the RBD is a promising vaccine target to induce protective immunity against SARS-CoV-2 infection.
format	article
author	Young-Il Kim Dokyun Kim Kwang-Min Yu Hogyu David Seo Shin-Ae Lee Mark Anthony B. Casel Seung-Gyu Jang Stephanie Kim WooRam Jung Chih-Jen Lai Young Ki Choi Jae U. Jung
author_facet	Young-Il Kim Dokyun Kim Kwang-Min Yu Hogyu David Seo Shin-Ae Lee Mark Anthony B. Casel Seung-Gyu Jang Stephanie Kim WooRam Jung Chih-Jen Lai Young Ki Choi Jae U. Jung
author_sort	Young-Il Kim
title	Development of Spike Receptor-Binding Domain Nanoparticles as a Vaccine Candidate against SARS-CoV-2 Infection in Ferrets
title_short	Development of Spike Receptor-Binding Domain Nanoparticles as a Vaccine Candidate against SARS-CoV-2 Infection in Ferrets
title_full	Development of Spike Receptor-Binding Domain Nanoparticles as a Vaccine Candidate against SARS-CoV-2 Infection in Ferrets
title_fullStr	Development of Spike Receptor-Binding Domain Nanoparticles as a Vaccine Candidate against SARS-CoV-2 Infection in Ferrets
title_full_unstemmed	Development of Spike Receptor-Binding Domain Nanoparticles as a Vaccine Candidate against SARS-CoV-2 Infection in Ferrets
title_sort	development of spike receptor-binding domain nanoparticles as a vaccine candidate against sars-cov-2 infection in ferrets
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/28c7b10f0f2446b1a7fdbe067aabdadd
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Development of Spike Receptor-Binding Domain Nanoparticles as a Vaccine Candidate against SARS-CoV-2 Infection in Ferrets

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