Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells

Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells

Sensory hair cells from the mammalian inner ear do not regenerate. Here, the authors induce direct hair cell formation from mouse embryonic stem cells using a three-dimensional culture system and observe differentiation of Type I and Type II vestibular hair cells and establishment of synapses with n...

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Autores principales: Xiao-Ping Liu, Karl R. Koehler, Andrew M. Mikosz, Eri Hashino, Jeffrey R. Holt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/28d1e711fb1b4e9e9e08b5c469b3d2a3
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