Erythropoietin promotes hippocampal mitochondrial function and enhances cognition in mice

Robert Jacobs, Mostafa Aboouf, et al. examined the effect of erythropoietin (EPO) in hippocampal mitochondrial function and memory in two mouse models: one overexpressing EPO in the brain, and juvenile mice treated during three days with a high dose of intraperitoneal EPO. Their results suggest that...

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Autores principales: Robert A. Jacobs, Mostafa A. Aboouf, Christina Koester-Hegmann, Paola Muttathukunnel, Sofien Laouafa, Christian Arias-Reyes, Markus Thiersch, Jorge Soliz, Max Gassmann, Edith M. Schneider Gasser
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/28d43af59b814496ad5a6dc3b560f703
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spelling oai:doaj.org-article:28d43af59b814496ad5a6dc3b560f7032021-12-02T17:06:23ZErythropoietin promotes hippocampal mitochondrial function and enhances cognition in mice10.1038/s42003-021-02465-82399-3642https://doaj.org/article/28d43af59b814496ad5a6dc3b560f7032021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02465-8https://doaj.org/toc/2399-3642Robert Jacobs, Mostafa Aboouf, et al. examined the effect of erythropoietin (EPO) in hippocampal mitochondrial function and memory in two mouse models: one overexpressing EPO in the brain, and juvenile mice treated during three days with a high dose of intraperitoneal EPO. Their results suggest that erythropoietin in the neonatal brain may impact spatial memory by increasing mitochondrial content.Robert A. JacobsMostafa A. AbooufChristina Koester-HegmannPaola MuttathukunnelSofien LaouafaChristian Arias-ReyesMarkus ThierschJorge SolizMax GassmannEdith M. Schneider GasserNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-19 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Robert A. Jacobs
Mostafa A. Aboouf
Christina Koester-Hegmann
Paola Muttathukunnel
Sofien Laouafa
Christian Arias-Reyes
Markus Thiersch
Jorge Soliz
Max Gassmann
Edith M. Schneider Gasser
Erythropoietin promotes hippocampal mitochondrial function and enhances cognition in mice
description Robert Jacobs, Mostafa Aboouf, et al. examined the effect of erythropoietin (EPO) in hippocampal mitochondrial function and memory in two mouse models: one overexpressing EPO in the brain, and juvenile mice treated during three days with a high dose of intraperitoneal EPO. Their results suggest that erythropoietin in the neonatal brain may impact spatial memory by increasing mitochondrial content.
format article
author Robert A. Jacobs
Mostafa A. Aboouf
Christina Koester-Hegmann
Paola Muttathukunnel
Sofien Laouafa
Christian Arias-Reyes
Markus Thiersch
Jorge Soliz
Max Gassmann
Edith M. Schneider Gasser
author_facet Robert A. Jacobs
Mostafa A. Aboouf
Christina Koester-Hegmann
Paola Muttathukunnel
Sofien Laouafa
Christian Arias-Reyes
Markus Thiersch
Jorge Soliz
Max Gassmann
Edith M. Schneider Gasser
author_sort Robert A. Jacobs
title Erythropoietin promotes hippocampal mitochondrial function and enhances cognition in mice
title_short Erythropoietin promotes hippocampal mitochondrial function and enhances cognition in mice
title_full Erythropoietin promotes hippocampal mitochondrial function and enhances cognition in mice
title_fullStr Erythropoietin promotes hippocampal mitochondrial function and enhances cognition in mice
title_full_unstemmed Erythropoietin promotes hippocampal mitochondrial function and enhances cognition in mice
title_sort erythropoietin promotes hippocampal mitochondrial function and enhances cognition in mice
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/28d43af59b814496ad5a6dc3b560f703
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AT christinakoesterhegmann erythropoietinpromoteshippocampalmitochondrialfunctionandenhancescognitioninmice
AT paolamuttathukunnel erythropoietinpromoteshippocampalmitochondrialfunctionandenhancescognitioninmice
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