Microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging

Weiwei Guan,1,* Wei Gu,2,* Ling Ye,2 Chenyang Guo,1 Su Su,1 Pinxiang Xu,1,3 Ming Xue1,3 1Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, People’s Republic of China; 2Department of Chemical Biology, School of Chemical Biology and Pharmace...

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Autores principales:	Guan WW, Gu W, Ye L, Guo CY, Su S, Xu PX, Xue M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/28de9df99a304156999bfa8c839721c3
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spelling	oai:doaj.org-article:28de9df99a304156999bfa8c839721c32021-12-02T05:36:18ZMicrowave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging1178-2013https://doaj.org/article/28de9df99a304156999bfa8c839721c32014-10-01T00:00:00Zhttp://www.dovepress.com/microwave-assisted-polyol-synthesis-of-carbon-nitride-dots-from-folic--peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013 Weiwei Guan,1,* Wei Gu,2,* Ling Ye,2 Chenyang Guo,1 Su Su,1 Pinxiang Xu,1,3 Ming Xue1,3 1Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, People’s Republic of China; 2Department of Chemical Biology, School of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Beijing, People’s Republic of China; 3Beijing Laboratory for Biomedical Detection Technology and Instrument, Beijing, People’s Republic of China *These authors contributed equally to this work Abstract: A green, one-step microwave-assisted polyol synthesis was employed to prepare blue luminescent carbon nitride dots (CNDs) using folic acid molecules as both carbon and nitrogen sources. The as-prepared CNDs had an average size of around 4.51 nm and could be well dispersed in water. Under excitation at 360 nm, the CNDs exhibited a strong blue luminescence and the quantum yield was estimated to be 18.9%, which is greater than that of other reported CNDs. Moreover, the CNDs showed low cytotoxicity and could efficiently label C6 glioma cells, demonstrating their potential in cell imaging. Keywords: carbon nitride dots (CNDs), folic acid, photoluminescence, cell imagingGuan WWGu WYe LGuo CYSu SXu PXXue MDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2014, Iss Issue 1, Pp 5071-5078 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Guan WW Gu W Ye L Guo CY Su S Xu PX Xue M Microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging
description	Weiwei Guan,1,* Wei Gu,2,* Ling Ye,2 Chenyang Guo,1 Su Su,1 Pinxiang Xu,1,3 Ming Xue1,3 1Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, People’s Republic of China; 2Department of Chemical Biology, School of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Beijing, People’s Republic of China; 3Beijing Laboratory for Biomedical Detection Technology and Instrument, Beijing, People’s Republic of China *These authors contributed equally to this work Abstract: A green, one-step microwave-assisted polyol synthesis was employed to prepare blue luminescent carbon nitride dots (CNDs) using folic acid molecules as both carbon and nitrogen sources. The as-prepared CNDs had an average size of around 4.51 nm and could be well dispersed in water. Under excitation at 360 nm, the CNDs exhibited a strong blue luminescence and the quantum yield was estimated to be 18.9%, which is greater than that of other reported CNDs. Moreover, the CNDs showed low cytotoxicity and could efficiently label C6 glioma cells, demonstrating their potential in cell imaging. Keywords: carbon nitride dots (CNDs), folic acid, photoluminescence, cell imaging
format	article
author	Guan WW Gu W Ye L Guo CY Su S Xu PX Xue M
author_facet	Guan WW Gu W Ye L Guo CY Su S Xu PX Xue M
author_sort	Guan WW
title	Microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging
title_short	Microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging
title_full	Microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging
title_fullStr	Microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging
title_full_unstemmed	Microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging
title_sort	microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/28de9df99a304156999bfa8c839721c3
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_version_	1718400283932884992

Microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging

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