Chromosomal Rearrangements and Altered Nuclear Organization: Recent Mechanistic Models in Cancer

Chromosomal Rearrangements and Altered Nuclear Organization: Recent Mechanistic Models in Cancer

The last decade has seen significant progress in understanding how the genome is organized spatially within interphase nuclei. Recent analyses have confirmed earlier molecular cytogenetic studies on chromosome positioning within interphase nuclei and provided new information about the topologically...

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Bibliographic Details
Main Authors: Concetta Federico, Francesca Bruno, Denise Ragusa, Craig S. Clements, Desiree Brancato, Marianne P. Henry, Joanna M. Bridger, Sabrina Tosi, Salvatore Saccone
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
cancer
genome organization
chromosomal rearrangements
topologically associated domains
replication timing
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/28e2f2c3cdeb4c978b1d450bad5ca58b
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https://doaj.org/article/28e2f2c3cdeb4c978b1d450bad5ca58b

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