Prognosis and role of clinical and imaging features in patients with malignant pericardial effusion: a single-center study in China

Abstract Background The diagnosis of malignant pericardial effusion (MPE) is often associated with a poor prognosis, but due to the complexity and unspecific nature of MPE patients' clinical manifestations, imaging often performs an essential role in diagnosis and prognosis. Methods Patients di...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Shucai Wang, Jiazheng Zhao, Chanchan Wang, Ning Zhang
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Malignant pericardial effusion Clinical features Imaging performance Treatment Prognosis Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/28ec8e8a8fe34f4580e0c58d5abbe520
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:28ec8e8a8fe34f4580e0c58d5abbe520
record_format	dspace
spelling	oai:doaj.org-article:28ec8e8a8fe34f4580e0c58d5abbe5202021-11-28T12:05:23ZPrognosis and role of clinical and imaging features in patients with malignant pericardial effusion: a single-center study in China10.1186/s12872-021-02331-91471-2261https://doaj.org/article/28ec8e8a8fe34f4580e0c58d5abbe5202021-11-01T00:00:00Zhttps://doi.org/10.1186/s12872-021-02331-9https://doaj.org/toc/1471-2261Abstract Background The diagnosis of malignant pericardial effusion (MPE) is often associated with a poor prognosis, but due to the complexity and unspecific nature of MPE patients' clinical manifestations, imaging often performs an essential role in diagnosis and prognosis. Methods Patients diagnosed with MPE between 2013 and 2018 at one tumor hospital were included and followed up. The data covered the basic clinical features, imaging findings, treatments and prognosis of patients with MPE, and the factors that may have affected the prognosis were explored. Results A total of 216 patients with MPE were included with the median age of 60 years. The most common primary cancer type was lung cancer (73.6%), the most common symptom was dyspnea (62.9%) and the most common abnormal electrocardiogram finding was sinus tachycardia (42.1%). The median survival time of the 216 patients with MPE was 13.7 months. The factors affecting prognosis were echocardiographic fluid signs (HR = 2.37, P = 0.010), electrocardiographic evidence of sinus tachycardia (HR = 1.76, P = 0.006) and echocardiographic evidence of cardiac tamponade (HR = 3.33, P < 0.001). Conclusions MPE has complex clinical manifestations and an unsatisfactory prognosis. Echocardiographic fluid signs, electrocardiographic evidence of sinus tachycardia, and echocardiographic evidence of cardiac tamponade are independent risk factors affecting prognosis.Shucai WangJiazheng ZhaoChanchan WangNing ZhangBMCarticleMalignant pericardial effusionClinical featuresImaging performanceTreatmentPrognosisDiseases of the circulatory (Cardiovascular) systemRC666-701ENBMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Malignant pericardial effusion Clinical features Imaging performance Treatment Prognosis Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Malignant pericardial effusion Clinical features Imaging performance Treatment Prognosis Diseases of the circulatory (Cardiovascular) system RC666-701 Shucai Wang Jiazheng Zhao Chanchan Wang Ning Zhang Prognosis and role of clinical and imaging features in patients with malignant pericardial effusion: a single-center study in China
description	Abstract Background The diagnosis of malignant pericardial effusion (MPE) is often associated with a poor prognosis, but due to the complexity and unspecific nature of MPE patients' clinical manifestations, imaging often performs an essential role in diagnosis and prognosis. Methods Patients diagnosed with MPE between 2013 and 2018 at one tumor hospital were included and followed up. The data covered the basic clinical features, imaging findings, treatments and prognosis of patients with MPE, and the factors that may have affected the prognosis were explored. Results A total of 216 patients with MPE were included with the median age of 60 years. The most common primary cancer type was lung cancer (73.6%), the most common symptom was dyspnea (62.9%) and the most common abnormal electrocardiogram finding was sinus tachycardia (42.1%). The median survival time of the 216 patients with MPE was 13.7 months. The factors affecting prognosis were echocardiographic fluid signs (HR = 2.37, P = 0.010), electrocardiographic evidence of sinus tachycardia (HR = 1.76, P = 0.006) and echocardiographic evidence of cardiac tamponade (HR = 3.33, P < 0.001). Conclusions MPE has complex clinical manifestations and an unsatisfactory prognosis. Echocardiographic fluid signs, electrocardiographic evidence of sinus tachycardia, and echocardiographic evidence of cardiac tamponade are independent risk factors affecting prognosis.
format	article
author	Shucai Wang Jiazheng Zhao Chanchan Wang Ning Zhang
author_facet	Shucai Wang Jiazheng Zhao Chanchan Wang Ning Zhang
author_sort	Shucai Wang
title	Prognosis and role of clinical and imaging features in patients with malignant pericardial effusion: a single-center study in China
title_short	Prognosis and role of clinical and imaging features in patients with malignant pericardial effusion: a single-center study in China
title_full	Prognosis and role of clinical and imaging features in patients with malignant pericardial effusion: a single-center study in China
title_fullStr	Prognosis and role of clinical and imaging features in patients with malignant pericardial effusion: a single-center study in China
title_full_unstemmed	Prognosis and role of clinical and imaging features in patients with malignant pericardial effusion: a single-center study in China
title_sort	prognosis and role of clinical and imaging features in patients with malignant pericardial effusion: a single-center study in china
publisher	BMC
publishDate	2021
url	https://doaj.org/article/28ec8e8a8fe34f4580e0c58d5abbe520
work_keys_str_mv	AT shucaiwang prognosisandroleofclinicalandimagingfeaturesinpatientswithmalignantpericardialeffusionasinglecenterstudyinchina AT jiazhengzhao prognosisandroleofclinicalandimagingfeaturesinpatientswithmalignantpericardialeffusionasinglecenterstudyinchina AT chanchanwang prognosisandroleofclinicalandimagingfeaturesinpatientswithmalignantpericardialeffusionasinglecenterstudyinchina AT ningzhang prognosisandroleofclinicalandimagingfeaturesinpatientswithmalignantpericardialeffusionasinglecenterstudyinchina
_version_	1718408188843261952

Prognosis and role of clinical and imaging features in patients with malignant pericardial effusion: a single-center study in China

Ejemplares similares