Quantitative Proteomics Reveals that Hsp90 Inhibition Dynamically Regulates Global Protein Synthesis in Leishmania mexicana

QR Code

Quantitative Proteomics Reveals that Hsp90 Inhibition Dynamically Regulates Global Protein Synthesis in Leishmania mexicana

Leishmania

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Karunakaran Kalesh, Sandeep Sundriyal, Hirunika Perera, Steven L. Cobb, Paul W. Denny
Format:	article
Langue:	EN
Publié:	American Society for Microbiology 2021
Sujets:	Microbiology QR1-502
Accès en ligne:	https://doaj.org/article/28f6e8711ef14f7aad5c7a6da02e3952
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Ribosome Profiling Reveals HSP90 Inhibitor Effects on Stage-Specific Protein Synthesis in <italic toggle="yes">Leishmania donovani</italic>
par: Eugenia Bifeld, et autres
Publié: (2018)

Hsp90 Inhibition: A Promising Therapeutic Approach for ARSACS
par: Suran Nethisinghe, et autres
Publié: (2021)

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome
par: Niina Piippo, et autres
Publié: (2018)

HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation
par: Toshiki Kijima, et autres
Publié: (2018)

HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes
par: Rina M. Mbofung, et autres
Publié: (2017)

Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90
par: Guohua Zhang, et autres
Publié: (2017)

Characteristic and expression of Hsp70 and Hsp90 genes from Tyrophagus putrescentiae and their response to thermal stress
par: Jing Wang, et autres
Publié: (2021)

Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells.
par: Morgan C Hunter, et autres
Publié: (2014)

Thermodynamics of aryl-dihydroxyphenyl-thiadiazole binding to human Hsp90.
par: Egidijus Kazlauskas, et autres
Publié: (2012)

Identification of HSP90 inhibitors as a novel class of senolytics
par: Heike Fuhrmann-Stroissnigg, et autres
Publié: (2017)

HSP-90/kinase complexes are stabilized by the large PPIase FKB-6
par: Siyuan Sima, et autres
Publié: (2021)

Conformational dynamics modulate the catalytic activity of the molecular chaperone Hsp90
par: Sophie L. Mader, et autres
Publié: (2020)

Human calmodulin methyltransferase: expression, activity on calmodulin, and Hsp90 dependence.
par: Sophia Magen, et autres
Publié: (2012)

Association between HSP90 and Her2 in gastric and gastroesophageal carcinomas.
par: Sabina Berezowska, et autres
Publié: (2013)

The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells
par: Manuel Schuster, et autres
Publié: (2017)

Proteomic analysis of proteome and histone post-translational modifications in heat shock protein 90 inhibition-mediated bladder cancer therapeutics
par: Qingdi Quentin Li, et autres
Publié: (2017)

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation
par: Kaushik Bhattacharya, et autres
Publié: (2020)

The expression patterns of HSP70 and HSP90 genes of abalone (Haliotis squamata) using 2-phenoxyethanol as an anaesthetic during transportation
par: Yasa Ngurah S., et autres
Publié: (2021)

Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex
par: Javier Oroz, et autres
Publié: (2018)

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus
par: Luke Whitesell, et autres
Publié: (2019)

The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range
par: Hannah Girstmair, et autres
Publié: (2019)

A switch point in the molecular chaperone Hsp90 responding to client interaction
par: Daniel Andreas Rutz, et autres
Publié: (2018)

Glucose Transporters and Virulence in <italic toggle="yes">Leishmania mexicana</italic>
par: Xiuhong Feng, et autres
Publié: (2018)

The Antileukemic Effect of Xestoquinone, A Marine-Derived Polycyclic Quinone-Type Metabolite, Is Mediated through ROS-Induced Inhibition of HSP-90
par: Kuan-Chih Wang, et autres
Publié: (2021)

Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor
par: Anuj Khandelwal, et autres
Publié: (2018)

An HSP90 cochaperone Ids2 maintains the stability of mitochondrial DNA and ATP synthase
par: Pei-Heng Jiang, et autres
Publié: (2021)

HSP90 as a novel molecular target in non-small-cell lung cancer
par: Esfahani K, et autres
Publié: (2016)

Hsp90 Is Essential for Chl1-Mediated Chromosome Segregation and Sister Chromatid Cohesion
par: Nidhi Khurana, et autres
Publié: (2018)

A methylated lysine is a switch point for conformational communication in the chaperone Hsp90
par: Alexandra Rehn, et autres
Publié: (2020)

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
par: Mark R. Woodford, et autres
Publié: (2016)

Nematode CDC-37 and DNJ-13 form complexes and can interact with HSP-90
par: Lukas Schmauder, et autres
Publié: (2021)

HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors
par: Kwon-Ho Song, et autres
Publié: (2020)

Author Correction: Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations
par: Julia A. Yaglom, et autres
Publié: (2018)

HSP90 and HSP70 Families in Lateolabrax maculatus: Genome-Wide Identification, Molecular Characterization, and Expression Profiles in Response to Various Environmental Stressors
par: Yalong Sun, et autres
Publié: (2021)

Human chemokines as antimicrobial peptides with direct parasiticidal effect on Leishmania mexicana in vitro.
par: Sara K Söbirk, et autres
Publié: (2013)

Extracellular heat shock protein (Hsp)70 and Hsp90α assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion.
par: Jessica D Sims, et autres
Publié: (2011)

The molecular chaperone Hsp90α is required for meiotic progression of spermatocytes beyond pachytene in the mouse.
par: Iwona Grad, et autres
Publié: (2010)

The HSP90/R2TP assembly chaperone promotes cell proliferation in the intestinal epithelium
par: Chloé Maurizy, et autres
Publié: (2021)

Heat-activated nanomedicine formulation improves the anticancer potential of the HSP90 inhibitor luminespib in vitro
par: Brittany Epp-Ducharme, et autres
Publié: (2021)

HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons
par: Sarah Kishinevsky, et autres
Publié: (2018)