Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species

Candida auris is an emergent fungal pathogen that is resistant to multiple antifungals. Here, Muñoz et al. analyse genomic sequences for isolates from each of the four major C. auris clades and for three related species, and identify genetic features associated with virulence, antifungal resistance...

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Autores principales: José F. Muñoz, Lalitha Gade, Nancy A. Chow, Vladimir N. Loparev, Phalasy Juieng, Elizabeth L. Berkow, Rhys A. Farrer, Anastasia P. Litvintseva, Christina A. Cuomo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/28fad645359b4b4b9e6b3f364031c465
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Sumario:Candida auris is an emergent fungal pathogen that is resistant to multiple antifungals. Here, Muñoz et al. analyse genomic sequences for isolates from each of the four major C. auris clades and for three related species, and identify genetic features associated with virulence, antifungal resistance and mating.