Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation

Systematic analysis of the control of dynamic cellular processes remains a challenge. Here the authors introduce a pipeline enabling them to identify TFs involved in Src-induced cellular transformation, and find that a large number of TFs with diverse DNA binding specificities orchestrate the proces...

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Autores principales:	Zhe Ji, Lizhi He, Asaf Rotem, Andreas Janzer, Christine S. Cheng, Aviv Regev, Kevin Struhl
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/290b03e8292f4574bc8968e5aeb70019
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spelling	oai:doaj.org-article:290b03e8292f4574bc8968e5aeb700192021-12-02T16:49:34ZGenome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation10.1038/s41467-018-04406-22041-1723https://doaj.org/article/290b03e8292f4574bc8968e5aeb700192018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04406-2https://doaj.org/toc/2041-1723Systematic analysis of the control of dynamic cellular processes remains a challenge. Here the authors introduce a pipeline enabling them to identify TFs involved in Src-induced cellular transformation, and find that a large number of TFs with diverse DNA binding specificities orchestrate the process.Zhe JiLizhi HeAsaf RotemAndreas JanzerChristine S. ChengAviv RegevKevin StruhlNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhe Ji Lizhi He Asaf Rotem Andreas Janzer Christine S. Cheng Aviv Regev Kevin Struhl Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation
description	Systematic analysis of the control of dynamic cellular processes remains a challenge. Here the authors introduce a pipeline enabling them to identify TFs involved in Src-induced cellular transformation, and find that a large number of TFs with diverse DNA binding specificities orchestrate the process.
format	article
author	Zhe Ji Lizhi He Asaf Rotem Andreas Janzer Christine S. Cheng Aviv Regev Kevin Struhl
author_facet	Zhe Ji Lizhi He Asaf Rotem Andreas Janzer Christine S. Cheng Aviv Regev Kevin Struhl
author_sort	Zhe Ji
title	Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation
title_short	Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation
title_full	Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation
title_fullStr	Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation
title_full_unstemmed	Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation
title_sort	genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/290b03e8292f4574bc8968e5aeb70019
work_keys_str_mv	AT zheji genomescaleidentificationoftranscriptionfactorsthatmediateaninflammatorynetworkduringbreastcellulartransformation AT lizhihe genomescaleidentificationoftranscriptionfactorsthatmediateaninflammatorynetworkduringbreastcellulartransformation AT asafrotem genomescaleidentificationoftranscriptionfactorsthatmediateaninflammatorynetworkduringbreastcellulartransformation AT andreasjanzer genomescaleidentificationoftranscriptionfactorsthatmediateaninflammatorynetworkduringbreastcellulartransformation AT christinescheng genomescaleidentificationoftranscriptionfactorsthatmediateaninflammatorynetworkduringbreastcellulartransformation AT avivregev genomescaleidentificationoftranscriptionfactorsthatmediateaninflammatorynetworkduringbreastcellulartransformation AT kevinstruhl genomescaleidentificationoftranscriptionfactorsthatmediateaninflammatorynetworkduringbreastcellulartransformation
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Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation

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