Role of <named-content content-type="genus-species">Plasmodium falciparum</named-content> Kelch 13 Protein Mutations in <named-content content-type="genus-species">P. falciparum</named-content> Populations from Northeastern Myanmar in Mediating Artemisinin Resistance

Role of <named-content content-type="genus-species">Plasmodium falciparum</named-content> Kelch 13 Protein Mutations in <named-content content-type="genus-species">P. falciparum</named-content> Populations from Northeastern Myanmar in Mediating Artemisinin Resistance

ABSTRACT Mutations in the Plasmodium falciparum Kelch 13 (PfK13) protein are associated with artemisinin resistance. PfK13 is essential for asexual erythrocytic development, but its function is not known. We tagged the PfK13 protein with green fluorescent protein in P. falciparum to study its expres...

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Autores principales: Faiza Amber Siddiqui, Rachasak Boonhok, Mynthia Cabrera, Huguette Gaelle Ngassa Mbenda, Meilian Wang, Hui Min, Xiaoying Liang, Junling Qin, Xiaotong Zhu, Jun Miao, Yaming Cao, Liwang Cui
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
PfK13
Plasmodium falciparum
artemisinin resistance
China-Myanmar border
mutations
drug resistance
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/291752193fb94113a77ef2dd1b6713c5
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