IMMUNITY AND DYNAMICS OF INFECTIONS IN HERPESVIRUS-CARRYING PREGNANT WOMEN WITH UNDIFFERENTIATED FORMS OF CONNECTIVE TISSUE DYSPLASIA HERPES VIRUSES

Abstract. We have studied some immune parameters in pregnant women with undifferentiated forms of connective tissue dysplasia (n = 51), who harboured herpesviruses, i.e., cytomegalovirus and Herpes Simplex virus. A relative insufficiency of CD3+ lymphocytes, along with deficiency of CD4+T cells, and...

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Autor principal:	L. N. Dorohova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	connective tissue displasia pregnancy herpes simplex virus cytomegalovirus immunit Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/29264cfe1ea64127a47789339a81c54d
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spelling	oai:doaj.org-article:29264cfe1ea64127a47789339a81c54d2021-11-18T08:03:41ZIMMUNITY AND DYNAMICS OF INFECTIONS IN HERPESVIRUS-CARRYING PREGNANT WOMEN WITH UNDIFFERENTIATED FORMS OF CONNECTIVE TISSUE DYSPLASIA HERPES VIRUSES1563-06252313-741X10.15789/1563-0625-2011-2-3-175-180https://doaj.org/article/29264cfe1ea64127a47789339a81c54d2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/453https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. We have studied some immune parameters in pregnant women with undifferentiated forms of connective tissue dysplasia (n = 51), who harboured herpesviruses, i.e., cytomegalovirus and Herpes Simplex virus. A relative insufficiency of CD3+ lymphocytes, along with deficiency of CD4+T cells, and predominance of CD16+ cells (NK cells), and CD20+ cells were revealed, accompanied by increase in IgM and the decrease in IgA and IgG levels. Disturbances of cellular and humoral immunity in such patients were more expressed than in women without undifferentiated forms of connective tissue dysplasia (n = 50), being associated with increased frequency of infection manifesting as inflammatory placental lesion with secondary placental insufficiency and more pessimistic perinatal outcomes. The results obtained justify a need for second preventive measures in pregnant, herpesvirus-carrying women with undifferentiated connective tissue dysplasia. (Med. Immunol., 2011, vol. 13, N 2-3, pp 175-180)L. N. DorohovaSPb RAACIarticleconnective tissue displasiapregnancyherpes simplex viruscytomegalovirusimmunitImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 13, Iss 2-3, Pp 175-180 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	connective tissue displasia pregnancy herpes simplex virus cytomegalovirus immunit Immunologic diseases. Allergy RC581-607
spellingShingle	connective tissue displasia pregnancy herpes simplex virus cytomegalovirus immunit Immunologic diseases. Allergy RC581-607 L. N. Dorohova IMMUNITY AND DYNAMICS OF INFECTIONS IN HERPESVIRUS-CARRYING PREGNANT WOMEN WITH UNDIFFERENTIATED FORMS OF CONNECTIVE TISSUE DYSPLASIA HERPES VIRUSES
description	Abstract. We have studied some immune parameters in pregnant women with undifferentiated forms of connective tissue dysplasia (n = 51), who harboured herpesviruses, i.e., cytomegalovirus and Herpes Simplex virus. A relative insufficiency of CD3+ lymphocytes, along with deficiency of CD4+T cells, and predominance of CD16+ cells (NK cells), and CD20+ cells were revealed, accompanied by increase in IgM and the decrease in IgA and IgG levels. Disturbances of cellular and humoral immunity in such patients were more expressed than in women without undifferentiated forms of connective tissue dysplasia (n = 50), being associated with increased frequency of infection manifesting as inflammatory placental lesion with secondary placental insufficiency and more pessimistic perinatal outcomes. The results obtained justify a need for second preventive measures in pregnant, herpesvirus-carrying women with undifferentiated connective tissue dysplasia. (Med. Immunol., 2011, vol. 13, N 2-3, pp 175-180)
format	article
author	L. N. Dorohova
author_facet	L. N. Dorohova
author_sort	L. N. Dorohova
title	IMMUNITY AND DYNAMICS OF INFECTIONS IN HERPESVIRUS-CARRYING PREGNANT WOMEN WITH UNDIFFERENTIATED FORMS OF CONNECTIVE TISSUE DYSPLASIA HERPES VIRUSES
title_short	IMMUNITY AND DYNAMICS OF INFECTIONS IN HERPESVIRUS-CARRYING PREGNANT WOMEN WITH UNDIFFERENTIATED FORMS OF CONNECTIVE TISSUE DYSPLASIA HERPES VIRUSES
title_full	IMMUNITY AND DYNAMICS OF INFECTIONS IN HERPESVIRUS-CARRYING PREGNANT WOMEN WITH UNDIFFERENTIATED FORMS OF CONNECTIVE TISSUE DYSPLASIA HERPES VIRUSES
title_fullStr	IMMUNITY AND DYNAMICS OF INFECTIONS IN HERPESVIRUS-CARRYING PREGNANT WOMEN WITH UNDIFFERENTIATED FORMS OF CONNECTIVE TISSUE DYSPLASIA HERPES VIRUSES
title_full_unstemmed	IMMUNITY AND DYNAMICS OF INFECTIONS IN HERPESVIRUS-CARRYING PREGNANT WOMEN WITH UNDIFFERENTIATED FORMS OF CONNECTIVE TISSUE DYSPLASIA HERPES VIRUSES
title_sort	immunity and dynamics of infections in herpesvirus-carrying pregnant women with undifferentiated forms of connective tissue dysplasia herpes viruses
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/29264cfe1ea64127a47789339a81c54d
work_keys_str_mv	AT lndorohova immunityanddynamicsofinfectionsinherpesviruscarryingpregnantwomenwithundifferentiatedformsofconnectivetissuedysplasiaherpesviruses
_version_	1718422469124030464

IMMUNITY AND DYNAMICS OF INFECTIONS IN HERPESVIRUS-CARRYING PREGNANT WOMEN WITH UNDIFFERENTIATED FORMS OF CONNECTIVE TISSUE DYSPLASIA HERPES VIRUSES

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