Habitual fish intake negatively correlates with prevalence of frailty among patients with rheumatoid arthritis
Abstract Frailty is a geriatric syndrome characterized by anabolic-catabolic imbalance and multisystem dysregulation resulting in increased adverse health outcomes, and is closely related with dietary habits in the general population. Although chronic inflammatory diseases are thought to accelerate...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/29321b3f00a14556aabd7c6c6f62d21d |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:29321b3f00a14556aabd7c6c6f62d21d |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:29321b3f00a14556aabd7c6c6f62d21d2021-12-02T13:30:52ZHabitual fish intake negatively correlates with prevalence of frailty among patients with rheumatoid arthritis10.1038/s41598-021-84479-02045-2322https://doaj.org/article/29321b3f00a14556aabd7c6c6f62d21d2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84479-0https://doaj.org/toc/2045-2322Abstract Frailty is a geriatric syndrome characterized by anabolic-catabolic imbalance and multisystem dysregulation resulting in increased adverse health outcomes, and is closely related with dietary habits in the general population. Although chronic inflammatory diseases are thought to accelerate development of frailty, correlations between rheumatoid arthritis (RA), frailty and dietary habits have not been examined. We performed a cross-sectional study using our cohort database (KURAMA cohort), and classified 306 participants into three groups (robust, prefrail and frail) according to the Study of Osteoporotic Fracture (SOF) criteria. Multivariate logistic analysis revealed that the presence of frailty/prefrailty was significantly correlated with the disease activity score (DAS28-ESR) (OR 1.70 (1.30–2.22), p < 0.0001). Additional analyses of frailty and food intake showed that 5 foods (fish, meat, milk, vegetables and fruits) of 20 groups on the questionnaire were inversely associated with the prevalence of frail/prefrail categories. In multivariate analysis with the five nutrients, fish intake (> two times a week) was an independent covariate negatively correlated with frailty/prefrailty (OR 0.35 (0.19–0.63), p = 0.00060). In conclusion, habitual fish intake may play a key role in nutritional intervention to prevent progression of frailty and RA.Hiroto MinaminoMasao KatsushimaMie ToriiMotomu HashimotoYoshihito FujitaKaori IkedaWataru YamamotoRyu WatanabeKosaku MurakamiKoichi MurataKohei NishitaniMasao TanakaHiromu ItoKoichiro OhmuraHidenori AraiNobuya InagakiShuichi MatsudaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Hiroto Minamino Masao Katsushima Mie Torii Motomu Hashimoto Yoshihito Fujita Kaori Ikeda Wataru Yamamoto Ryu Watanabe Kosaku Murakami Koichi Murata Kohei Nishitani Masao Tanaka Hiromu Ito Koichiro Ohmura Hidenori Arai Nobuya Inagaki Shuichi Matsuda Habitual fish intake negatively correlates with prevalence of frailty among patients with rheumatoid arthritis |
| description |
Abstract Frailty is a geriatric syndrome characterized by anabolic-catabolic imbalance and multisystem dysregulation resulting in increased adverse health outcomes, and is closely related with dietary habits in the general population. Although chronic inflammatory diseases are thought to accelerate development of frailty, correlations between rheumatoid arthritis (RA), frailty and dietary habits have not been examined. We performed a cross-sectional study using our cohort database (KURAMA cohort), and classified 306 participants into three groups (robust, prefrail and frail) according to the Study of Osteoporotic Fracture (SOF) criteria. Multivariate logistic analysis revealed that the presence of frailty/prefrailty was significantly correlated with the disease activity score (DAS28-ESR) (OR 1.70 (1.30–2.22), p < 0.0001). Additional analyses of frailty and food intake showed that 5 foods (fish, meat, milk, vegetables and fruits) of 20 groups on the questionnaire were inversely associated with the prevalence of frail/prefrail categories. In multivariate analysis with the five nutrients, fish intake (> two times a week) was an independent covariate negatively correlated with frailty/prefrailty (OR 0.35 (0.19–0.63), p = 0.00060). In conclusion, habitual fish intake may play a key role in nutritional intervention to prevent progression of frailty and RA. |
| format |
article |
| author |
Hiroto Minamino Masao Katsushima Mie Torii Motomu Hashimoto Yoshihito Fujita Kaori Ikeda Wataru Yamamoto Ryu Watanabe Kosaku Murakami Koichi Murata Kohei Nishitani Masao Tanaka Hiromu Ito Koichiro Ohmura Hidenori Arai Nobuya Inagaki Shuichi Matsuda |
| author_facet |
Hiroto Minamino Masao Katsushima Mie Torii Motomu Hashimoto Yoshihito Fujita Kaori Ikeda Wataru Yamamoto Ryu Watanabe Kosaku Murakami Koichi Murata Kohei Nishitani Masao Tanaka Hiromu Ito Koichiro Ohmura Hidenori Arai Nobuya Inagaki Shuichi Matsuda |
| author_sort |
Hiroto Minamino |
| title |
Habitual fish intake negatively correlates with prevalence of frailty among patients with rheumatoid arthritis |
| title_short |
Habitual fish intake negatively correlates with prevalence of frailty among patients with rheumatoid arthritis |
| title_full |
Habitual fish intake negatively correlates with prevalence of frailty among patients with rheumatoid arthritis |
| title_fullStr |
Habitual fish intake negatively correlates with prevalence of frailty among patients with rheumatoid arthritis |
| title_full_unstemmed |
Habitual fish intake negatively correlates with prevalence of frailty among patients with rheumatoid arthritis |
| title_sort |
habitual fish intake negatively correlates with prevalence of frailty among patients with rheumatoid arthritis |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/29321b3f00a14556aabd7c6c6f62d21d |
| work_keys_str_mv |
AT hirotominamino habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT masaokatsushima habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT mietorii habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT motomuhashimoto habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT yoshihitofujita habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT kaoriikeda habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT wataruyamamoto habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT ryuwatanabe habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT kosakumurakami habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT koichimurata habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT koheinishitani habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT masaotanaka habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT hiromuito habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT koichiroohmura habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT hidenoriarai habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT nobuyainagaki habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis AT shuichimatsuda habitualfishintakenegativelycorrelateswithprevalenceoffrailtyamongpatientswithrheumatoidarthritis |
| _version_ |
1718392904669462528 |